C₄₁H₅₂O₉

Base Information

Chemical Name:C₄₁H₅₂O₉
CAS No.:457064-35-6
Molecular Formula:C₄₁H₅₂O₉
Molecular Weight:688.858
Hs Code.:

C<sub>41</sub>H<sub>52</sub>O<sub>9</sub>

Synonyms:C₄₁H₅₂O₉

Suppliers and Price of C₄₁H₅₂O₉

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₁H₅₂O₉

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₁H₅₂O₉

There total 14 articles about C₄₁H₅₂O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 77-76-9
2,2-dimethoxy-propane

: (2R,3S,4R,5aR,7S,8R,10S,11R,12aS)-4,8-Bis-benzyloxy-7-benzyloxymethyl-2-hydroxymethyl-dodecahydro-1,6-dioxa-cycloheptacyclononene-3,10,11-triol

: 457064-35-6
C₄₁H₅₂O₉

Guidance literature:: In dichloromethane; at 20 ℃; for 0.333333h;
DOI:10.1021/ol026306n

Reference yield:

: 457064-30-1
(Z)-6-((2R,4aR,6S,7R,9R,9aS)-9-Benzyloxy-7-hydroxy-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl)-hex-4-enoic acid

: 457064-35-6
C₄₁H₅₂O₉

Guidance literature:: Multi-step reaction with 13 steps

1.1: 2,4,6-Cl₃C₆H₂COCl; Et₃N / tetrahydrofuran / 20 °C

1.2: 71 percent / DMAP / benzene / 80 °C

2.1: 6.39 g / potassium hexamethyldisilazide; hexamethylphosphoric triamide / tetrahydrofuran; toluene / 0.67 h / -78 °C

3.1: 76 percent / triethylamine / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide / 15 h / 50 °C

4.1: AD mix-α; methanesulfonamide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 48 h / 20 °C

5.1: 79 percent / 10-camphorsulfonic acid / CH₂Cl₂ / 1 h / 20 °C

6.1: DIBALH / CH₂Cl₂; toluene / 0.5 h / -78 °C

7.1: 2,6-lutidine / CH₂Cl₂ / 0 - 20 °C

8.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / -20 °C

9.1: 75 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.33 h / 0 °C

10.1: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C

11.1: 98 percent / potassium tert-butoxide / tetrahydrofuran / 0.42 h / 20 °C

12.1: ethanethiol; zinc triflate / CH₂Cl₂ / 26 h / 20 °C

13.1: 78 percent / CH₂Cl₂ / 0.33 h / 20 °C

With 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; AD-mix-α; borane-THF; methanesulfonamide; 2,4,6-trichlorobenzoyl chloride; (1S)-10-camphorsulfonic acid; potassium tert-butylate; tetrabutyl ammonium fluoride; 3,3-dimethyldioxirane; potassium hexamethylsilazane; zinc trifluoromethanesulfonate; diisobutylaluminium hydride; triethylamine; ethanethiol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol;
DOI:10.1021/ol026306n

Reference yield:

: 457064-29-8
(Z)-6-((2R,4aR,6S,7R,9R,9aS)-9-Benzyloxy-2-phenyl-7-triethylsilanyloxy-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl)-hex-4-enoic acid ethyl ester

: 457064-35-6
C₄₁H₅₂O₉

Guidance literature:: Multi-step reaction with 14 steps

1.1: Ba(OH)2*8H₂O / dioxane; H₂O / 60 °C

1.2: 88 percent / CSA / CH₂Cl₂; methanol / 20 °C

2.1: 2,4,6-Cl₃C₆H₂COCl; Et₃N / tetrahydrofuran / 20 °C

2.2: 71 percent / DMAP / benzene / 80 °C

3.1: 6.39 g / potassium hexamethyldisilazide; hexamethylphosphoric triamide / tetrahydrofuran; toluene / 0.67 h / -78 °C

4.1: 76 percent / triethylamine / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide / 15 h / 50 °C

5.1: AD mix-α; methanesulfonamide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 48 h / 20 °C

6.1: 79 percent / 10-camphorsulfonic acid / CH₂Cl₂ / 1 h / 20 °C

7.1: DIBALH / CH₂Cl₂; toluene / 0.5 h / -78 °C

8.1: 2,6-lutidine / CH₂Cl₂ / 0 - 20 °C

9.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / -20 °C

10.1: 75 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.33 h / 0 °C

11.1: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C

12.1: 98 percent / potassium tert-butoxide / tetrahydrofuran / 0.42 h / 20 °C

13.1: ethanethiol; zinc triflate / CH₂Cl₂ / 26 h / 20 °C

14.1: 78 percent / CH₂Cl₂ / 0.33 h / 20 °C

With 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; barium dihydroxide; AD-mix-α; borane-THF; methanesulfonamide; 2,4,6-trichlorobenzoyl chloride; (1S)-10-camphorsulfonic acid; potassium tert-butylate; tetrabutyl ammonium fluoride; 3,3-dimethyldioxirane; potassium hexamethylsilazane; zinc trifluoromethanesulfonate; diisobutylaluminium hydride; triethylamine; ethanethiol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol;
DOI:10.1021/ol026306n