(1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol

Base Information

• Chemical Name: (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol
• CAS No.: 120444-22-6
• Molecular Formula: C₃₄H₃₅FO₅
• Molecular Weight: 542.647
• Mol file: 120444-22-6.mol

Synonyms:(1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol

Chemical Property of (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol

There total 20 articles about (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

DL-2-O-Benzoyl-3,4,5,6-tetra-O-benzyl-1-deoxy-1-fluoro-scyllo-inositol (85716-58-1,97335-91-6,97335-92-7,97335-93-8) → (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol (85747-85-9,97335-94-9,97335-95-0,97335-96-1,120444-19-1,120444-21-5,120444-22-6,120444-23-7,129707-22-8)

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Ambient temperature;

DOI:10.1039/p19960001845

Reference yield: 90.0%

Benzoic acid (1S,2R,3S,4S,5R,6S)-2,3,4,5-tetrakis-benzyloxy-6-fluoro-cyclohexyl ester (172722-80-4) → (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol (120444-22-6)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1016/0040-4039(95)01579-5

Reference yield: 90.0%

(1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid (1S,2R,3S,4S,5R,6S)-2,3,4,5-tetrakis-benzyloxy-6-fluoro-cyclohexyl ester (120444-20-4) → (1S,2S,3R,4S,5R,6R)-2,3,4,5-Tetrakis-benzyloxy-6-fluoro-cyclohexanol (120444-22-6)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1039/c39880001301

upstream raw materials:

rac-1,4,5,6-tetra-O-benzyl-myo-inositol

(+/-)-1-O-p-toluenesulfonyl-3,4,5,6-tetra-O-benzyl-myo-inositol

DL-2,3,4,5-Tetra-O-benzyl-1-deoxy-1-fluoro-6-O-tosyl-scyllo-inositol

DL-2-O-Benzoyl-3,4,5,6-tetra-O-benzyl-1-deoxy-1-fluoro-scyllo-inositol

Downstream raw materials:

(-)-1D-3,4,5,6-Tetra-O-benzyl-1-deoxy-1-fluoro-myo-inositol

(+)-1L-3,4,5,6-Tetra-O-benzyl-1-deoxy-1-fluoro-myo-inositol

Hexadecanoic acid 2-[((1R,2R,3S,4R,5R,6S)-2-fluoro-3,4,5,6-tetrahydroxy-cyclohexyloxy)-hydroxy-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester

Hexadecanoic acid 2-[((1S,2S,3R,4S,5S,6R)-2-fluoro-3,4,5,6-tetrahydroxy-cyclohexyloxy)-hydroxy-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester