2-fluoro-N-phenylbenzimidamide

Base Information

• Chemical Name: 2-fluoro-N-phenylbenzimidamide
• CAS No.: 21719-75-5
• Molecular Formula: C₁₃H₁₁FN₂
• Molecular Weight: 214.242
• Mol file: 21719-75-5.mol

Synonyms:2-fluoro-N-phenylbenzimidamide

Chemical Property of 2-fluoro-N-phenylbenzimidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-fluoro-N-phenylbenzimidamide

There total 2 articles about 2-fluoro-N-phenylbenzimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluorobenzonitrile (394-47-8) + aniline (62-53-3) → 2-fluoro-N-phenylbenzimidamide (21719-75-5)

Guidance literature:

With aluminum (III) chloride; at 200 ℃; for 0.5h;

DOI:10.1021/ol502302w

Reference yield:

→ 2-fluoro-N-phenylbenzimidamide (21719-75-5)

Guidance literature:

o-Fluorbenzaldehydphenylhydrazon, NaNH2, Erhitzen;

Reference yield: 98.0%

4-toluenesulfonyl azide (941-55-9) + 1-(buta-1,3-diyn-1-yl)naphthalene (31067-48-8) + 2-fluoro-N-phenylbenzimidamide (21719-75-5) → (E)-N-(2-(2-fluorophenyl)-6-(naphthalen-1-ylmethyl)-3-phenylpyrimidin-4(3H)-ylidene)-4-methylbenzenesulfonamide

Guidance literature:

With triethylamine; copper(l) chloride; In 1,2-dichloro-ethane; at 20 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1021/ol502302w

upstream raw materials:

2-fluorobenzonitrile

aniline

Downstream raw materials:

2-phenyl-3-phenylisoquinolin-1-one