C₁₈H₁₇FN₄O₂S

Base Information

Chemical Name:C₁₈H₁₇FN₄O₂S
CAS No.:1426683-51-3
Molecular Formula:C₁₈H₁₇FN₄O₂S
Molecular Weight:372.423
Hs Code.:

C<sub>18</sub>H<sub>17</sub>FN<sub>4</sub>O<sub>2</sub>S

Synonyms:C₁₈H₁₇FN₄O₂S

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Chemical Property of C₁₈H₁₇FN₄O₂S

Chemical Property:

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Technology Process of C₁₈H₁₇FN₄O₂S

There total 5 articles about C₁₈H₁₇FN₄O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1426683-50-2
1,5-dimethyl-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-amine 4,4-dioxide

: 459-57-4
4-fluorobenzaldehyde

: 1426683-51-3
C₁₈H₁₇FN₄O₂S

Guidance literature:: 1,5-dimethyl-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-amine 4,4-dioxide; 4-fluorobenzaldehyde; With acetic acid; In N,N-dimethyl acetamide; acetonitrile; at 20 ℃; for 4h;

With sodium tetrahydroborate; In N,N-dimethyl acetamide; acetonitrile; at 20 ℃; for 14h;
DOI:10.1016/j.bmcl.2013.01.047

Reference yield:

: 2965-22-2
methyl 2-fluoro-5-nitro-benzoate

: 1426683-51-3
C₁₈H₁₇FN₄O₂S

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / dimethyl sulfoxide / 2 h / 20 °C

2.1: sodium hydride / mineral oil; N,N-dimethyl acetamide / 2 h / 0 - 20 °C

2.2: Cooling with ice

3.1: tetrahydrofuran / 2 h / 0 - 20 °C

3.2: 3 h / Reflux

4.1: hydrogen; palladium 10% on activated carbon / methanol; acetonitrile / 3 h / 20 °C

5.1: acetic acid / N,N-dimethyl acetamide; acetonitrile / 4 h / 20 °C

5.2: 14 h / 20 °C

With palladium 10% on activated carbon; hydrogen; sodium hydride; potassium carbonate; acetic acid; In tetrahydrofuran; methanol; N,N-dimethyl acetamide; dimethyl sulfoxide; acetonitrile; mineral oil;
DOI:10.1016/j.bmcl.2013.01.047

Reference yield:

: 1426683-32-0
methyl 2-[methyl(methylsulfonyl)amino]-5-nitrobenzoate

: 1426683-51-3
C₁₈H₁₇FN₄O₂S

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / mineral oil; N,N-dimethyl acetamide / 2 h / 0 - 20 °C

1.2: Cooling with ice

2.1: tetrahydrofuran / 2 h / 0 - 20 °C

2.2: 3 h / Reflux

3.1: hydrogen; palladium 10% on activated carbon / methanol; acetonitrile / 3 h / 20 °C

4.1: acetic acid / N,N-dimethyl acetamide; acetonitrile / 4 h / 20 °C

4.2: 14 h / 20 °C

With palladium 10% on activated carbon; hydrogen; sodium hydride; acetic acid; In tetrahydrofuran; methanol; N,N-dimethyl acetamide; acetonitrile; mineral oil;
DOI:10.1016/j.bmcl.2013.01.047