sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate

Base Information

Chemical Name:sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate
CAS No.:127166-41-0
Molecular Formula:C26H22 N2 O3 . Na
Molecular Weight:432.454
Hs Code.:
Mol file:127166-41-0.mol

Synonyms:Dibenz[b,e]oxepin-2-carboxylicacid, 11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydro-,sodium salt, (E)-; KW 3635

Suppliers and Price of sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate

Chemical Property:

Vapor Pressure:8.13E-19mmHg at 25°C
Boiling Point:669.1°C at 760 mmHg
Flash Point:358.5°C

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate

There total 18 articles about sodium (11E)-11-[2-(5,6-dimethyl-1H-benzimidazol-1-yl)ethylidene]-6,11-dihydrodibenzo[b,e]oxepine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 127165-95-1
(E)-11-<2-(5,6-dimethyl-1-benzimidazoyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylic acid methyl ester

: 127166-41-0
sodium (E)-11-<2-(5,6-dimethyl-1-benzimidazolyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate monohydrate

Guidance literature:: With sodium hydroxide; In methanol; water; at 60 ℃;

Reference yield:

: 95-64-7
4-amino-o-xylene

: 127166-41-0
sodium (E)-11-<2-(5,6-dimethyl-1-benzimidazolyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate monohydrate

Guidance literature:: Multi-step reaction with 10 steps

1: acetic acid; H₂O / 1 h / 60 °C

2: 70 percent aq. HNO₃, AcOH / 1 h / below 15 deg C

3: KOH, water / methanol / 1 h / 60 °C

4: 91 percent / Ac₂O / 0.5 h / 60 °C

5: 91 percent / H₂ / 5percent Pd/C / 2-methoxy-ethanol / 3 h / 70 °C / 7600 Torr

6: CH₂Cl₂ / 1 h / Heating

7: MeSO₃H / propan-2-ol / 1 h / 70 °C

8: NaBH₄ / tetrahydrofuran; methanol / 1 h / 40 °C

9: formic acid / tetrahydrofuran; methanol / 1 h / 60 °C

10: 10 N aq. NaOH / methanol; tetrahydrofuran / 1 h / 60 °C

With potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; formic acid; methanesulfonic acid; water; hydrogen; nitric acid; acetic anhydride; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; 2-methoxy-ethanol; water; acetic acid; isopropyl alcohol;
DOI:10.1055/s-1995-4088

Reference yield:

: 6970-77-0
N-(4,5-dimethyl-2-nitrophenyl)acetamide

: 127166-41-0
sodium (E)-11-<2-(5,6-dimethyl-1-benzimidazolyl)ethylidene>-6,11-dihydrodibenzoxepin-2-carboxylate monohydrate

Guidance literature:: Multi-step reaction with 8 steps

1: KOH, water / methanol / 1 h / 60 °C

2: 91 percent / Ac₂O / 0.5 h / 60 °C

3: 91 percent / H₂ / 5percent Pd/C / 2-methoxy-ethanol / 3 h / 70 °C / 7600 Torr

4: CH₂Cl₂ / 1 h / Heating

5: MeSO₃H / propan-2-ol / 1 h / 70 °C

6: NaBH₄ / tetrahydrofuran; methanol / 1 h / 40 °C

7: formic acid / tetrahydrofuran; methanol / 1 h / 60 °C

8: 10 N aq. NaOH / methanol; tetrahydrofuran / 1 h / 60 °C

With potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; formic acid; methanesulfonic acid; water; hydrogen; acetic anhydride; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; 2-methoxy-ethanol; isopropyl alcohol;
DOI:10.1055/s-1995-4088