Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride

Base Information

Chemical Name:Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride
CAS No.:1828-12-2
Molecular Formula:C14H18FNO
Molecular Weight:271.762
Hs Code.:
European Community (EC) Number:669-263-2
NSC Number:49041
DSSTox Substance ID:DTXSID70171332
Mol file:1828-12-2.mol

Synonyms:1828-12-2;CN HCl;1-(4-fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride;Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride;NSC 49041;4'-Fluoro-3-piperidinopropiophenone hydrochloride;4'-Fluoro-3-(1-piperidyl)propiophenone hydrochloride;1-(4-fluorophenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride;1-Propanone, 1-(4-fluorophenyl)-3-(1-piperidinyl)-, hydrochloride;C14H18FNO.ClH;DTXSID70171332;BAA82812;NSC49041;NSC-49041;1-(4-FLUOROPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;AKOS024321071;LS-125302;EN300-152711;1-(4-fluorophenyl)-3-(piperidin-1-yl)propan-1-onehydrochloride

Suppliers and Price of Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride

Chemical Property:

Vapor Pressure:4.11E-05mmHg at 25°C
Boiling Point:351.4°C at 760 mmHg
Flash Point:166.3°C
Density:1.093g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:271.1139201
Heavy Atom Count:18
Complexity:243

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CCC(=O)C2=CC=C(C=C2)F.Cl

Technology Process of Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride

There total 1 articles about Propiophenone, 4'-fluoro-3-piperidino-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 6091-44-7
piperidine hydrochloride

: 403-42-9
1-(4-fluorophenyl)ethanone

: 1828-12-2
1-(4-Fluoro-phenyl)-3-piperidin-1-yl-propan-1-one; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 8h; Heating;

Reference yield: 12.0%

: 1828-12-2
1-(4-Fluoro-phenyl)-3-piperidin-1-yl-propan-1-one; hydrochloride

: N,N'-bis[1-(4-fluorophenyl)-3-(piperidine-1-yl)propylidene]hydrazine dihydrochloride

Guidance literature:: With hydrazine hydrate; acetic acid; In ethanol; at 20 ℃; for 26h;
DOI:10.3109/14756366.2013.795562

Reference yield:

: 1828-12-2
1-(4-Fluoro-phenyl)-3-piperidin-1-yl-propan-1-one; hydrochloride

: 4'-fluoro-2,3-dihydro-[1,1'-biphenyl]-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1) sodium ethoxide, 2) dimethyl sulphate / 1) ethanol, 2) 5 deg C, 1 h, 20 deg C, 6 h

2: 71.5 percent / sodium carbonate / ethanol; H₂O / 20 h / Heating

With sodium ethanolate; sodium carbonate; dimethyl sulfate; In ethanol; water;