2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME

Base Information

• Chemical Name: 2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME
• CAS No.: 129083-51-8
• Molecular Formula: C₉H₁₀N₂O₃
• Molecular Weight: 194.19
• Mol file: 129083-51-8.mol

Synonyms:2-hydroxy-5-methyl-1,3-benzenedicarboxaldehyde-1,3-dioxime

Chemical Property of 2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME

Chemical Property:

Purity/Quality:

2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME

There total 2 articles about 2-HYDROXY-5-METHYLISOPHTHALALDEHYDE DIOXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Hydroxy-5-methylisophthalaldehyde (7310-95-4) → 2-hydroxy-5-methyl-1,3-benzenedicarboxaldehyde-1,3-dioxime (129083-51-8)

Guidance literature:

With hydroxylamine hydrochloride; In dimethyl sulfoxide;

DOI:10.1016/j.tetlet.2011.07.070

Reference yield:

p-cresol (106-44-5) → 2-hydroxy-5-methyl-1,3-benzenedicarboxaldehyde-1,3-dioxime (129083-51-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / 20 h / 0 - 85 °C / Inert atmosphere

1.2: 20 °C

2.1: hydroxylamine hydrochloride / dimethyl sulfoxide

With hydroxylamine hydrochloride; trifluoroacetic acid; In dimethyl sulfoxide; 1.1: Duff reaction;

DOI:10.1016/j.tetlet.2011.07.070

Reference yield: 90.0%

2-hydroxy-5-methyl-1,3-benzenedicarboxaldehyde-1,3-dioxime (129083-51-8) + copper diacetate (142-71-2) → 2Cu(2+)*2C9H8N2O3(2-) = [Cu2(C9H8N2O3)2]

Guidance literature:

In N,N-dimethyl-formamide; stirring (room temp., overnight); elem. anal.;

DOI:10.1039/a807031h

upstream raw materials:

p-cresol

2-Hydroxy-5-methylisophthalaldehyde

Downstream raw materials:

2-hydroxy-5-methylisophthalonitrile

(S)-2-hydroxy-3-(4-isopropyl-4,5-dihydrooxazol-2-yl)-5-methylbenzonitrile

3-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)-2-hydroxy-5-methylbenzonitrile