2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

Base Information

Chemical Name:2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt
CAS No.:1016651-03-8
Molecular Formula:C₂HF₃O₂*C₂₁H₂₈F₂N₄O₆
Molecular Weight:584.497
Hs Code.:

2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

Synonyms:2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

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Chemical Property of 2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

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Technology Process of 2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

There total 2 articles about 2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1016651-09-4
(S)-N-{3-[3,5-difluoro-4-(4-(S)-2-tert-butoxycarbonylamino-methyl-4-methoxymethyl-piperidine-1-yl)phenyl]-2-oxo-oxazolidin-5-yl methyl}-acetamide

: 76-05-1
trifluoroacetic acid

: 1016651-03-8
2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

Guidance literature:: In dichloromethane; at 20 ℃; Inert atmosphere;

Reference yield:

: 957796-51-9
(5S)-N-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

: 1016651-03-8
2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: dicyclohexyl-carbodiimide / dichloromethane / 0.5 h / 0 - 5 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: dichloromethane / 20 °C / Inert atmosphere

With dicyclohexyl-carbodiimide; In dichloromethane;