957796-51-9

Upstream product

• 67-56-1 methanol 
• 1207472-10-3 [3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-carbamic acid benzyl ester 
• 183905-31-9 N-[(2S)-2-acetoxy-3-chloropropyl]acetamide 
• 1207472-08-9 1-(2,6-difluoro-4-nitrophenyl)-4-methoxymethyl-piperidin-4-ol 
• 1207472-09-0 6-(2,6-difluoro-4-nitrophenyl)-1-oxa-6-azaspiro[2.5]octane 
• 1207472-12-5 (5R)-3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-5-azidomethyl-oxazolidin-2-one 
• 1207472-07-8 (5R)-methanesulfonic acid 3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 1207472-06-7 (5R)-3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-5-hydroxymethyl-oxazolidin-2-one 
• 1207472-11-4 1-(4-amino-2,6-difluoro-phenyl)-4-methoxymethyl-piperidin-4-ol 
• 565459-90-7 1-(2,6-difluoro-4-nitrophenyl)piperidin-4-one 
• 66684-58-0 3,4,5-trifluoronitrobenzene 
• 41979-39-9 4-piperidone hydrochloride 
• 60-35-5 acetamide 
• 1207472-13-6 5-aminomethyl-3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-oxazolidin-2-one 

Downstream Products

• 957796-52-0 (5S)-N-{3-[3,5-difluoro-4-(4-fluoro-(4-methoxymethyl)-piperidin-1yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 1016651-04-9 (S)-2-amino-3,3-dimethylpropionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester methanesulfonic acid salt 
• 1016651-10-7 (S)-N-{3-[3,5-difluoro-4-(4-((S)-2-carbobenzyloxyamino-3,3-dimethylpropionyl)-4-methoxymethyl-piperidine-1-yl)phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide 
• 1016651-09-4 (S)-N-{3-[3,5-difluoro-4-(4-(S)-2-tert-butoxycarbonylamino-methyl-4-methoxymethyl-piperidine-1-yl)phenyl]-2-oxo-oxazolidin-5-yl methyl}-acetamide 
• 1016650-95-5 (S)-2-amino-propionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester trifluoroacetic acid salt 
• 1016650-92-2 (S)-2-amino-propionic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride 
• 1016651-03-8 2-amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester triflouroacetic acid salt 
• 1016650-88-6 phosphoric acid mono-(1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl) ester L-lysine salt 
• 1016650-87-5 phosphoric acid mono-(1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl) ester L-arginine salt 
• 1016650-82-0 phosphoric acid mono-(1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl) ester 
• 1016651-01-6 2-Amino-acetic acid 1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluorophenyl}-4-methoxymethyl-piperidin-4-yl ester hydrochloride salt 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF (5S)-N-{3-[3,5-DIFLUORO-4-(4-HYDROXY-4-METHOXYMETHYL-PIPERIDIN-1-YL)-PHENYL]-2-OXO-OXAZOLIDIN-5-YLMETHYL}-ACETAMIDE

A process for preparation of compound of Formula (I) is provided.

PROCESS FOR THE PREPARATION OF PHOSPHORIC ACID MONO- (L-{4- [(S) -5- (ACETYLAMINOMETHYL) - 2 - OXO - OXAZOLIDIN- 3 - YL] - 2, 6 - DIFLUOROPHENYL} - 4 -METHOXYMETHYLPIPERIDIN- 4 - YL) ESTER

The invention relates to a process to prepare pharmacologically active phosphoric acid mono-(1-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2,6-difluoro phenyl}-4-methoxy methyl-piperidin-4-yl) ester.

SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES

The present invention relates to certain substituted piperidino phenyloxazolidinones. Specifically, the invention relates to geminally disubstituted piperidino phenyloxazolidinones having antimicrobial activity with improved pharmacokinetic profile. The i