3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester

Base Information

• Chemical Name: 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester
• CAS No.: 178552-54-0
• Molecular Formula: C₃₆H₅₉N₃O₁₀
• Molecular Weight: 693.879
• Mol file: 178552-54-0.mol

Synonyms:3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester

Chemical Property of 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester

There total 3 articles about 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H19N3O2 (1040797-40-7) + bromoacetic acid tert-butyl ester (5292-43-3) → 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester (178552-54-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1039/b717390c

Reference yield:

1,7-Bis(trifluoroacetyl)-4-benzyloxycarbonyl-1,4,7-triazaheptane (178552-53-9) → 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester (178552-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; ethanol

2: potassium carbonate / N,N-dimethyl-formamide

With ethanol; potassium carbonate; sodium hydroxide; In N,N-dimethyl-formamide;

DOI:10.1007/s00775-013-1036-y

Reference yield:

→ 3,9-Bis(tert-butoxycarbonylmethyl)-6-benzyloxycarbonyl-3,6,9-triazaundecanedicarboxylic acid-di-tert-butyl ester (178552-54-0)

Guidance literature:

upstream raw materials:

C₁₂H₁₉N₃O₂

bromoacetic acid tert-butyl ester

1,7-Bis(trifluoroacetyl)-4-benzyloxycarbonyl-1,4,7-triazaheptane