(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Base Information

Chemical Name:(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester
CAS No.:637741-41-4
Molecular Formula:C₆₇H₉₀O₁₂
Molecular Weight:1087.44
Hs Code.:

(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Synonyms:(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Suppliers and Price of (E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

There total 8 articles about (E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 637740-87-5
(1R,2S,3R)-1-[(4-methoxybenzyloxy)methyl]-2,3-bis(4-methoxybenzyloxy)-4-hydroxybutyl (2E)-2-methyl-3-[1,3-dimethyl-2-oxo-4-[(1E,3S,4R,5S)-1,3,5-trimethyl-4-(4-methoxybenzyloxy)-1-pentadecenyl]-3-cyclohexenyl]propenoate

: 637741-41-4
(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Guidance literature:: With pyridine; Dess-Martin periodane; In dichloromethane; at 20 ℃; for 1.5h;
DOI:10.1039/b305818b

Reference yield:

: 81465-44-3
3-Iodo-2,6-dimethyl-cyclohex-2-enone

: 637741-41-4
(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Guidance literature:: Multi-step reaction with 8 steps

1.1: 62 percent / aq. NaOH / dioxane / 0.5 h / 20 °C

2.1: 92 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / -78 - 20 °C

3.1: 97 percent / toluene / 20 h / Heating

4.1: 54 percent / iodotrimethylsilane / 5 h / Heating

5.1: 66 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; N,N-dimethylaminopyridine / CH₂Cl₂ / 5 h / Heating

6.1: 9-BBN / tetrahydrofuran / 24 h / 20 °C

6.2: K₃PO₄ / PdCl₂(dppf) / dimethylformamide; H₂O / 1 h / 50 °C

7.1: 61 mg / aq. HCl / tetrahydrofuran / 6 h / 20 °C

8.1: 90 percent / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 1.5 h / 20 °C

With pyridine; hydrogenchloride; dmap; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; oxalyl dichloride; trimethylsilyl iodide; Dess-Martin periodane; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; toluene; 2.1: Swern oxidation / 6.2: Suzuki-Miyaura coupling;
DOI:10.1039/b305818b

Reference yield:

: 637741-38-9
4-iodo-1,3-dimethyl-2-oxo-cyclohex-3-enecarbaldehyde

: 637741-41-4
(E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: 97 percent / toluene / 20 h / Heating

2.1: 54 percent / iodotrimethylsilane / 5 h / Heating

3.1: 66 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; N,N-dimethylaminopyridine / CH₂Cl₂ / 5 h / Heating

4.1: 9-BBN / tetrahydrofuran / 24 h / 20 °C

4.2: K₃PO₄ / PdCl₂(dppf) / dimethylformamide; H₂O / 1 h / 50 °C

5.1: 61 mg / aq. HCl / tetrahydrofuran / 6 h / 20 °C

6.1: 90 percent / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 1.5 h / 20 °C

With pyridine; hydrogenchloride; dmap; 9-borabicyclo[3.3.1]nonane dimer; trimethylsilyl iodide; Dess-Martin periodane; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; toluene; 4.2: Suzuki-Miyaura coupling;
DOI:10.1039/b305818b