tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate

Base Information

• Chemical Name: tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate
• CAS No.: 1108147-63-2
• Molecular Formula: C₃₁H₅₀N₄O₃
• Molecular Weight: 526.763
• Mol file: 1108147-63-2.mol

Synonyms:tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate

Chemical Property of tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate

There total 1 articles about tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine (1108147-58-5) + (R)-1-Boc-nipecotic acid (163438-09-3) → tert-butyl (3R)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}phenyl)amino]carbonyl}-1-piperidinecarboxylate (1108147-63-2)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at -30 - 20 ℃; Inert atmosphere;

DOI:10.1021/jm7012979

upstream raw materials:

N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine

(R)-1-Boc-nipecotic acid