N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine

Base Information

• Chemical Name: N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine
• CAS No.: 1108147-58-5
• Molecular Formula: C₂₀H₃₃N₃
• Molecular Weight: 315.502
• Mol file: 1108147-58-5.mol

Synonyms:N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine

Chemical Property of N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine

There total 2 articles about N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(1-methylcyclooctyl)-N-(2-nitrophenyl)piperidin-4-amine (1108147-62-1) → N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine (1108147-58-5)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; methanol; water; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1021/jm7012979

Reference yield:

→ N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine (1108147-58-5)

Guidance literature:

Reference yield: 64.0%

N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine (1108147-58-5) + ethyl 2-(3-formylphenoxy)acetate (51264-68-7) → ethyl (3-{1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenoxy)acetate (1108147-84-7)

Guidance literature:

N-[1-(1-methylcyclooctyl)-4-piperidinyl]-1,2-benzenediamine; ethyl 2-(3-formylphenoxy)acetate; In ethanol; for 1h; Inert atmosphere; Reflux;

With lead(IV) tetraacetate; In benzene; for 1h; Reflux;

DOI:10.1021/jm7012979

upstream raw materials:

1-(1-methylcyclooctyl)-N-(2-nitrophenyl)piperidin-4-amine

Downstream raw materials:

ethyl (3-{1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenoxy)acetate

1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[3-(trifluoromethyl)phenyl]-1H-benzimidazole

3-{1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}benzonitrile

tert-butyl (3S)-3-{[(2-{[1-(1-methylcyclooctyl)-4-piperidinyl]amino}-phenyl)amino]carbonyl}-1-piperidinecarboxylate