Robalzotan

Base Information

Chemical Name:Robalzotan
CAS No.:169758-66-1
Molecular Formula:C₁₈H₂₃FN₂O₂
Molecular Weight:318.391
Hs Code.:2932999099
UNII:I18M56OGME
DSSTox Substance ID:DTXSID30168743
Nikkaji Number:J900.925F
Wikipedia:Robalzotan
Wikidata:Q7340703
NCI Thesaurus Code:C74143
Pharos Ligand ID:K58V1K9Q2UA8
Metabolomics Workbench ID:149827
ChEMBL ID:CHEMBL1628569
Mol file:169758-66-1.mol

Synonyms:3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen tartrate monohydrate;NAD 299;NAD-299;robalzotan

Suppliers and Price of Robalzotan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
NAD299hydrochloride ≥98%(HPLC)
50
$ 710.00

Tocris
NAD299hydrochloride ≥98%(HPLC)
10
$ 169.00

American Custom Chemicals Corporation
ROBALZOTAN 95.00%
50MG
$ 1327.97

American Custom Chemicals Corporation
ROBALZOTAN 95.00%
10MG
$ 721.59

Total 9 raw suppliers

Chemical Property of Robalzotan

Chemical Property:

Vapor Pressure:1.36E-07mmHg at 25°C
Boiling Point:429.9°C at 760 mmHg
PKA:15.72±0.40(Predicted)
Flash Point:213.8°C
PSA：179.85000
Density:1.27g/cm³
LogP:1.14850
Storage Temp.:Desiccate at RT
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:318.17435614
Heavy Atom Count:23
Complexity:438

Purity/Quality:

99% ^*data from raw suppliers

NAD299hydrochloride ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C1)N(C2CCC2)C3CC4=C(C=CC(=C4OC3)F)C(=O)N
Isomeric SMILES:C1CC(C1)N([C@@H]2CC3=C(C=CC(=C3OC2)F)C(=O)N)C4CCC4
Recent EU Clinical Trials:A double-blind randomized placebo controlled crossover study of AZD7371 ER 5 mg bid, 20 mg bid and placebo treatment for one week on visceral perception and symptoms in patients with Irritable Bowel Syndrome
Uses NAD 299 Hydrochloride is a selective, high affinity 5-HT1A antagonist, used in psychotropic drug development.

Technology Process of Robalzotan

There total 3 articles about Robalzotan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%