Technology Process of C15H18INO
There total 5 articles about C15H18INO which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C14H16INO;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
methyl iodide;
In
tetrahydrofuran; mineral oil;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ol402210a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydroxide; water / methanol / 1 h / Inert atmosphere; Reflux
2.1: diethylamine / ethyl acetate / 2 h / Inert atmosphere; Reflux
3.1: thionyl chloride / 0.5 h / 80 °C
4.1: dmap; triethylamine / dichloromethane / -20 - 20 °C / Inert atmosphere
5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C / Inert atmosphere
5.2: 2 h / 0 - 20 °C / Inert atmosphere
With
dmap; thionyl chloride; water; sodium hydride; diethylamine; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate; mineral oil;
DOI:10.1021/ol402210a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diethylamine / ethyl acetate / 2 h / Inert atmosphere; Reflux
2.1: thionyl chloride / 0.5 h / 80 °C
3.1: dmap; triethylamine / dichloromethane / -20 - 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C / Inert atmosphere
4.2: 2 h / 0 - 20 °C / Inert atmosphere
With
dmap; thionyl chloride; sodium hydride; diethylamine; triethylamine;
In
tetrahydrofuran; dichloromethane; ethyl acetate; mineral oil;
DOI:10.1021/ol402210a
