3,4-Dichloroisothiazole-5-carboxylic acid

Base Information

Chemical Name:3,4-Dichloroisothiazole-5-carboxylic acid
CAS No.:18480-53-0
Molecular Formula:C4HCl2NO2S
Molecular Weight:198.029
Hs Code.:2934999090
European Community (EC) Number:619-518-9
UNII:1C7254T4E6
DSSTox Substance ID:DTXSID7041467
Wikidata:Q27252224
ChEMBL ID:CHEMBL3183876
Mol file:18480-53-0.mol

Synonyms:3,4-dichloro-5-isothiazolecarboxylate;potassium 3,4-dichloro-5-isothiazolecarboxylate

Suppliers and Price of 3,4-Dichloroisothiazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dichloroisothiazole-5-carboxylicAcid
100mg
$ 75.00

SynQuest Laboratories
Dichloro-1,2-thiazole-5-carboxylic acid 98%
1 g
$ 160.00

Sigma-Aldrich
Isotianil PESTANAL?, analytical standard
100 mg
$ 102.00

Oakwood
3,4-Dichloroisothiazole-5-carboxylic acid
25g
$ 478.00

Oakwood
3,4-Dichloroisothiazole-5-carboxylic acid
10g
$ 238.00

Oakwood
3,4-Dichloroisothiazole-5-carboxylic acid
250mg
$ 20.00

Oakwood
3,4-Dichloroisothiazole-5-carboxylic acid
1g
$ 43.00

Oakwood
3,4-Dichloroisothiazole-5-carboxylic acid
5g
$ 148.00

Matrix Scientific
3,4-Dichloroisothiazole-5-carboxylic acid
1g
$ 218.00

Matrix Scientific
3,4-Dichloroisothiazole-5-carboxylic acid
10g
$ 972.00

Total 61 raw suppliers

Chemical Property of 3,4-Dichloroisothiazole-5-carboxylic acid

Chemical Property:

Vapor Pressure:0.147mmHg at 25°C
Melting Point:175-177 °C
Refractive Index:1.646
Boiling Point:205.9 °C at 760 mmHg
PKA:0.74±0.28(Predicted)
Flash Point:78.4 °C
PSA：78.43000
Density:1.824 g/cm³
LogP:2.14810
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:196.9105048
Heavy Atom Count:10
Complexity:156

Purity/Quality:

99.9% ^*data from raw suppliers

3,4-Dichloroisothiazole-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1(=C(SN=C1Cl)C(=O)O)Cl

Technology Process of 3,4-Dichloroisothiazole-5-carboxylic acid

There total 2 articles about 3,4-Dichloroisothiazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 18480-52-9
3,4-dichloro-5-cyanoisothiazole

: 18480-53-0
3,4-dichloro-isothiazole-5-carboxylic acid

Guidance literature:: With water; sodium hydroxide; for 6h; Reflux;
DOI:10.1134/S107042802010022X

Reference yield:

: 18480-53-0
3,4-dichloro-isothiazole-5-carboxylic acid

Guidance literature:

Reference yield: 97.0%

: 3218-02-8
cyclohexylmethylamine

: 18480-53-0
3,4-dichloro-isothiazole-5-carboxylic acid

: 3,4-dichloro-N-(cyclohexylmethyl)isothiazole-5-carboxamide

Guidance literature:: 3,4-dichloro-isothiazole-5-carboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;

cyclohexylmethylamine; With triethylamine; In dichloromethane; at 20 ℃; for 1h;