2-(4-Methoxybenzamido)propanoic acid

Base Information

Chemical Name:2-(4-Methoxybenzamido)propanoic acid
CAS No.:108462-96-0
Molecular Formula:C₁₁H₁₃NO₄
Molecular Weight:223.229
Hs Code.:
ChEMBL ID:CHEMBL8538

Synonyms:2-(4-Methoxybenzamido)propanoic acid;108462-96-0;CHEMBL8538;Oprea1_875980;SCHEMBL5637591;RWJPONNMYFWDLB-UHFFFAOYSA-N;2-(4-Methoxybenzamido)propanoicacid;AKOS000126581;AKOS016050979;SR-01000487843;SR-01000487843-1

Suppliers and Price of 2-(4-Methoxybenzamido)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Methoxybenzamido)propanoic acid

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:223.08445790
Heavy Atom Count:16
Complexity:259

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)O)NC(=O)C1=CC=C(C=C1)OC

Technology Process of 2-(4-Methoxybenzamido)propanoic acid

There total 6 articles about 2-(4-Methoxybenzamido)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2-(4-Methoxy-benzoylamino)-propionic acid ethyl ester

: 108462-96-0
DL-N-(4-methoxybenzoyl)alanine

Guidance literature:: 2-(4-Methoxy-benzoylamino)-propionic acid ethyl ester; With sodium hydroxide; In methanol; water; at 20 ℃; for 18h;

With hydrogenchloride; In methanol; water; at 0 ℃; pH=0 - 1;
DOI:10.1002/chem.201202455

Reference yield:

: 100-07-2
4-methoxy-benzoyl chloride

: 302-72-7,25191-17-7,18875-37-1
rac-Ala-OH

: 108462-96-0
DL-N-(4-methoxybenzoyl)alanine

Guidance literature:: With sodium hydroxide;
DOI:10.1021/jo50012a014

Reference yield:

: 100-09-4
4-methoxybenzoic acid

: 108462-96-0
DL-N-(4-methoxybenzoyl)alanine

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2, DMF / benzene / Ambient temperature

2: NaOH / H₂O / 70 - 80 °C

With sodium hydroxide; oxalyl dichloride; N,N-dimethyl-formamide; In water; benzene;
DOI:10.1021/jm00125a017