2,3,4-tribromoquinoline

Base Information

• Chemical Name: 2,3,4-tribromoquinoline
• CAS No.: 41320-97-2
• Molecular Formula: C₉H₄Br₃N
• Molecular Weight: 365.849
• Mol file: 41320-97-2.mol

Synonyms:2,3,4-tribromoquinoline

Chemical Property of 2,3,4-tribromoquinoline

Chemical Property:

• Melting Point: 288 °C
• Boiling Point: 383.5±37.0 °C(Predicted)
• PKA: -3.62±0.50(Predicted)
• Density: 2.212±0.06 g/cm3(Predicted)

Purity/Quality:

2,3,4-TRIBROMOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tribromoquinoline

There total 2 articles about 2,3,4-tribromoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3,4-dibromoquinoline (41320-96-1) → 2,3,4-tribromoquinoline (41320-97-2)

Guidance literature:

3,4-dibromoquinoline; In tetrahydrofuran; at -78 ℃; for 2h;

With 1,2-dibromo-1,1,2,2-tetrachloroethane; In tetrahydrofuran; at -78 - 20 ℃; for 12h; Further stages.;

DOI:10.1021/ol702494k

Reference yield:

→ 2,3,4-tribromoquinoline (41320-97-2)

Guidance literature:

2,4-Dihydroxychinolin, POBr3;

Reference yield: 89.0%

2,3,4-tribromoquinoline (41320-97-2) + benzyl bromide (100-39-0) → 3-benzyl-2,4-dibromoquinoline (1000007-18-0)

Guidance literature:

2,3,4-tribromoquinoline; With (mesityl)MgBr*LiCl; In tetrahydrofuran; at -10 ℃; for 3h;

benzyl bromide; In tetrahydrofuran; at -50 - 20 ℃; for 20.5h; Further stages.;

DOI:10.1021/ol702494k

upstream raw materials:

3,4-dibromoquinoline

Downstream raw materials:

3-benzyl-2,4-dibromoquinoline

Refernces