(3S)-methyl 3-amino-4-butanoate

Base Information

• Chemical Name: (3S)-methyl 3-amino-4-butanoate
• CAS No.: 229487-04-1
• Molecular Formula: C₁₃H₁₈N₂O₅
• Molecular Weight: 282.296
• Mol file: 229487-04-1.mol

Synonyms:(3S)-methyl 3-amino-4-butanoate

Chemical Property of (3S)-methyl 3-amino-4-butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S)-methyl 3-amino-4-butanoate

There total 10 articles about (3S)-methyl 3-amino-4-butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-benzyloxycarbonylamino-N-(2,5-dihydroxy-benzyl)-N-methyl-succinamic acid methyl ester (229487-01-8) → (3S)-methyl 3-amino-4-butanoate (229487-04-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1055/s-1999-3094

Reference yield:

N-(benzyloxycarbonyl)-L-aspartic acid 4-methyl ester (3160-47-2) → (3S)-methyl 3-amino-4-butanoate (229487-04-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / DCC

2: 70 percent / H₂ / 10 percent Pd/C / ethanol

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In ethanol;

DOI:10.1055/s-1999-3094

Reference yield:

2,5-Dihydroxybenzaldehyde (1194-98-5) → (3S)-methyl 3-amino-4-butanoate (229487-04-1)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol; toluene

2: H₂ / 10 percent Pd/C / ethanol

3: 46 percent / DCC

4: 70 percent / H₂ / 10 percent Pd/C / ethanol

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In ethanol; toluene;

DOI:10.1055/s-1999-3094

upstream raw materials:

3-benzyloxycarbonylamino-N-(3,6-dioxo-cyclohexa-1,4-dienylmethyl)-N-methyl-succinamic acid methyl ester

3-benzyloxycarbonylamino-N-(2,5-dihydroxy-benzyl)-N-methyl-succinamic acid methyl ester

2,5-Dihydroxybenzaldehyde

N-(benzyloxycarbonyl)-L-aspartic acid 4-methyl ester