1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole

Base Information

• Chemical Name: 1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole
• CAS No.: 124325-14-0
• Molecular Formula: C₁₇H₁₆ClN₃O₂S
• Molecular Weight: 361.852
• Mol file: 124325-14-0.mol

Synonyms:1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole

Chemical Property of 1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole

There total 1 articles about 1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1-(3-chlorophenyl)-3-methyl-1H-pyrazol-5-amine (40401-41-0) + benzenesulfonyl chloride (1939-99-7) → 1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole (124325-14-0)

Guidance literature:

With pyridine; for 2h; Heating;

Reference yield: 90.0%

1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole (124325-14-0) → 1-(3-Chlorophenyl)-3-methyl-4-nitroso-5-benzylsulfonamidopyrazole (124325-27-5)

Guidance literature:

With sodium nitrite; In acetic acid; for 0.166667h; Ambient temperature;

Reference yield:

1-(3-Chlorophenyl)-3-methyl-5-benzylsulfonamidopyrazole (124325-14-0) → 1-(3-chlorophenyl)-3-methyl-4-amino-5-benzylsulphonamidopyrazole (141497-80-5)

Guidance literature:

Multi-step reaction with 2 steps

1: nitrosation

2: 77 percent / hydrazin hydrate / 5percent palladized charcoal / methanol / 0.08 h / Heating

With hydrazine hydrate; palladium on activated charcoal; In methanol;

upstream raw materials:

1-(3-chlorophenyl)-3-methyl-1H-pyrazol-5-amine

benzenesulfonyl chloride

Downstream raw materials:

1-(3-Chlorophenyl)-3-methyl-4-nitroso-5-benzylsulfonamidopyrazole

1-(3-chlorophenyl)-3-methyl-4-amino-5-benzylsulphonamidopyrazole

1-(3-Chlorophenyl)-3-methyl-4-benzamido-5-aminopyrazole

3-phenyl-5-methyl-7-(3-chlorophenyl)-6,7-dihydropyrazolo<3,4-c><1,2,5>thiadiazine 2,2-dioxide