Technology Process of 1-[(E)-3-(4-[1,3]dioxolan-2-yl-2-methoxy-phenyl)-allyl]-pyrrolidine-2,5-dione
There total 3 articles about 1-[(E)-3-(4-[1,3]dioxolan-2-yl-2-methoxy-phenyl)-allyl]-pyrrolidine-2,5-dione which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium phosphate; potassium chloride; tetrabutylammomium bromide; palladium diacetate;
In
N,N-dimethyl-formamide;
at 120 ℃;
for 8h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 2 h / 20 °C
2: toluene-4-sulfonic acid / benzene / 180 °C
3: palladium diacetate; potassium chloride; tetrabutylammomium bromide; potassium phosphate / N,N-dimethyl-formamide / 8 h / 120 °C / Inert atmosphere
With
pyridine; potassium phosphate; potassium chloride; tetrabutylammomium bromide; palladium diacetate; toluene-4-sulfonic acid;
In
dichloromethane; N,N-dimethyl-formamide; benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / benzene / 180 °C
2: palladium diacetate; potassium chloride; tetrabutylammomium bromide; potassium phosphate / N,N-dimethyl-formamide / 8 h / 120 °C / Inert atmosphere
With
potassium phosphate; potassium chloride; tetrabutylammomium bromide; palladium diacetate; toluene-4-sulfonic acid;
In
N,N-dimethyl-formamide; benzene;