Technology Process of C19H18F3IN2O3S
There total 7 articles about C19H18F3IN2O3S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C19H16F3IN2O3S;
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
at 20 - 50 ℃;
for 16h;
Inert atmosphere;
With
sodium hydroxide;
In
tetrahydrofuran; water;
With
dihydrogen peroxide;
In
tetrahydrofuran; water;
at 20 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: nitric acid; acetic acid / 0.75 h / 4 - 20 °C
2.1: potassium carbonate / acetone / 2 h / Reflux
3.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C
3.2: 17 h / -78 - 20 °C
4.1: water; sodium dithionite / ethanol / 1 h / 90 °C
5.1: 20 °C / Inert atmosphere; Heating
6.1: Hoveyda-Grubbs catalyst second generation / 1,1-dichloroethane / 3 h / 70 °C
7.1: dimethylsulfide borane complex / tetrahydrofuran / 16 h / 20 - 50 °C / Inert atmosphere
7.3: 0.5 h / 20 °C
With
sodium dithionite; dimethylsulfide borane complex; water; nitric acid; potassium carbonate; acetic acid; lithium hexamethyldisilazane;
Hoveyda-Grubbs catalyst second generation;
In
tetrahydrofuran; 1,1-dichloroethane; ethanol; acetone;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / acetone / 2 h / Reflux
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C
2.2: 17 h / -78 - 20 °C
3.1: water; sodium dithionite / ethanol / 1 h / 90 °C
4.1: 20 °C / Inert atmosphere; Heating
5.1: Hoveyda-Grubbs catalyst second generation / 1,1-dichloroethane / 3 h / 70 °C
6.1: dimethylsulfide borane complex / tetrahydrofuran / 16 h / 20 - 50 °C / Inert atmosphere
6.3: 0.5 h / 20 °C
With
sodium dithionite; dimethylsulfide borane complex; water; potassium carbonate; lithium hexamethyldisilazane;
Hoveyda-Grubbs catalyst second generation;
In
tetrahydrofuran; 1,1-dichloroethane; ethanol; acetone;
