4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

Base Information

Chemical Name:4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide
CAS No.:943653-50-7
Molecular Formula:C₃₀H₃₆N₄O₃S₂Si
Molecular Weight:592.858
Hs Code.:

Synonyms:4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

Suppliers and Price of 4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

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Technology Process of 4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

There total 1 articles about 4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: (R)-2-(O-tert-butyldiphenylsilane)methyl-piperazine dihydrochloride

: 331972-47-5
4-bromo-N-(thiazol-2-yl)benzene sulfonamide

: 943653-50-7
4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

Guidance literature:: With johnphos; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 80 ℃; for 1h;

Reference yield:

: 943653-50-7
4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide

: 33995-30-1
(S)-2-(2,3-dichlorophenoxy)propionic acid

: 943653-51-8
(S)-2-(2,3-dichlorophenoxy)-1-((R)-2-(O-tert-butyldiphenylsilane)-4-(4-N-(thiazol-2-yl)benzenesulfonamide)piperazin-1-yl)propan-1-one

Guidance literature:: (S)-2-(2,3-dichlorophenoxy)propionic acid; With HATU; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

4-((R)-2-O-tert-butyldiphenylsilane)methyl-piperazine-N-(thiazol-2-yl)benzenesulfonamide; With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;