2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Base Information

Chemical Name:2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide
CAS No.:1308255-18-6
Molecular Formula:C₂₂H₂₂BN₃O₅S
Molecular Weight:451.311
Hs Code.:

Synonyms:2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Suppliers and Price of 2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

There total 8 articles about 2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1308254-89-8
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)acetic acid

: 100-46-9
benzylamine

: 1308255-18-6
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; for 3h;

Reference yield:

: 52913-11-8
(3-amino-phenyl)-acetic acid methyl ester

: 1308255-18-6
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Guidance literature:: Multi-step reaction with 5 steps

1: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C

2: chlorosulfonic acid / 2 h / 0 - 20 °C / Neat (no solvent)

3: 4-methyl-morpholine / acetonitrile / 0 - 20 °C

4: sodium hydroxide; water / methanol / 16 h / 20 °C

5: triethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 3 h

With 4-methyl-morpholine; 2,6-dimethylpyridine; chlorosulfonic acid; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; triethylamine; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 3958-57-4
1-bromomethyl-3-nitrobenzene

: 1308255-18-6
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)-N-benzylacetamide

Guidance literature:: Multi-step reaction with 8 steps

1: N,N-dimethyl-formamide / 5 h / 50 °C

2: hydrogenchloride / methanol / 20 °C

3: hydrogenchloride; iron / water; methanol / 20 °C

4: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C

5: chlorosulfonic acid / 2 h / 0 - 20 °C / Neat (no solvent)

6: 4-methyl-morpholine / acetonitrile / 0 - 20 °C

7: sodium hydroxide; water / methanol / 16 h / 20 °C

8: triethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 3 h

With 4-methyl-morpholine; 2,6-dimethylpyridine; hydrogenchloride; chlorosulfonic acid; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; iron; triethylamine; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;