2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid

Base Information

Chemical Name:2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid
CAS No.:1308254-89-8
Molecular Formula:C15H15BN2O6S
Molecular Weight:362.171
Hs Code.:

Synonyms:2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid

Suppliers and Price of 2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid

There total 7 articles about 2-(5-aMino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfaMoyl)phenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1308254-75-2
methyl 2-(2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)-5-(2,2,2-trifluoroacetamido)phenyl)acetate

: 1308254-89-8
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)acetic acid

Guidance literature:: methyl 2-(2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)-5-(2,2,2-trifluoroacetamido)phenyl)acetate; With water; sodium hydroxide; In methanol; at 20 ℃; for 16h;

With hydrogenchloride; In water; Product distribution / selectivity;

Reference yield:

: 52913-11-8
(3-amino-phenyl)-acetic acid methyl ester

: 1308254-89-8
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C

2: chlorosulfonic acid / 2 h / 0 - 20 °C / Neat (no solvent)

3: 4-methyl-morpholine / acetonitrile / 0 - 20 °C

4: sodium hydroxide; water / methanol / 16 h / 20 °C

With 4-methyl-morpholine; 2,6-dimethylpyridine; chlorosulfonic acid; water; sodium hydroxide; In methanol; dichloromethane; acetonitrile;

Reference yield:

: 3958-57-4
1-bromomethyl-3-nitrobenzene

: 1308254-89-8
2-(5-amino-2-(N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)sulfamoyl)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 7 steps

1: N,N-dimethyl-formamide / 5 h / 50 °C

2: hydrogenchloride / methanol / 20 °C

3: hydrogenchloride; iron / water; methanol / 20 °C

4: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C

5: chlorosulfonic acid / 2 h / 0 - 20 °C / Neat (no solvent)

6: 4-methyl-morpholine / acetonitrile / 0 - 20 °C

7: sodium hydroxide; water / methanol / 16 h / 20 °C

With 4-methyl-morpholine; 2,6-dimethylpyridine; hydrogenchloride; chlorosulfonic acid; water; iron; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;