(S)-(-)-PROPAFENONE HYDROCHLORIDE

Base Information

Chemical Name:(S)-(-)-PROPAFENONE HYDROCHLORIDE
CAS No.:107381-36-2
Molecular Formula:C21H27 N O3 . Cl H
Molecular Weight:377.91
Hs Code.:
Mol file:107381-36-2.mol

Synonyms:1-Propanone,1-[2-[(2S)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride(9CI); 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-,hydrochloride, (S)-; (S)-Propafenone hydrochloride; Lu 44216

Suppliers and Price of (S)-(-)-PROPAFENONE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (S)-(-)-PROPAFENONE HYDROCHLORIDE

Chemical Property:

Vapor Pressure:1.27E-11mmHg at 25°C
Boiling Point:519.6°Cat760mmHg
Flash Point:268°C
PSA：58.56000
Density:g/cm³
LogP:4.43430
Storage Temp.:2-8°C

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 46-22
Safety Statements: 53-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-(-)-PROPAFENONE HYDROCHLORIDE

There total 9 articles about (S)-(-)-PROPAFENONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: (2R-(2α(S*),3aα,4α,7α,7aα))-1-(2-(2-(2-Octahydro-7,8,8-trimethyl-4,7-methano-2-benzofuranyloxy)-3-propylamino-propoxy)-phenyl)-3-phenyl-1-propanon

: 107381-36-2
(S)-propafenone hydrochloride

Guidance literature:: With hydrogenchloride; methanol; In diethyl ether;
DOI:10.1002/ardp.19943271104

Reference yield:

: 3516-95-8
2'-hydroxy-3-phenylpropiophenone

: 107381-36-2
(S)-propafenone hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 62.8 percent / TsOH / benzene / 86 h / Heating

2: 90 percent / NaH / dimethylformamide / 3 h / 50 °C

3: 81 percent / 2 h / Heating

4: 2 N HCl / 1 h / 80 °C

With hydrogenchloride; sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; benzene;
DOI:10.1007/BF00807638

Reference yield:

: 189766-45-8
2-(2-phenethyl-1,3-dioxolan-2-yl)phenol

: 107381-36-2
(S)-propafenone hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NaH / dimethylformamide / 3 h / 50 °C

2: 81 percent / 2 h / Heating

3: 2 N HCl / 1 h / 80 °C

With hydrogenchloride; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1007/BF00807638