(3aR,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic

Base Information

• Chemical Name: (3aR,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic
• CAS No.: 122059-86-3
• Molecular Formula: C₁₉H₁₇NO₂
• Molecular Weight: 291.349
• Mol file: 122059-86-3.mol

Synonyms:4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid

Chemical Property of (3aR,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic

Chemical Property:

• Melting Point: 206-207 °C
• Boiling Point: 484.0±45.0 °C(Predicted)
• PKA: 4.89±0.40(Predicted)
• Density: 1.231±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

(3AR,4S,9BS)-4-PHENYL-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA[C]QUINOLINE-8-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of (3aR,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic

There total 5 articles about (3aR,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-Amino-benzoic acid; compound with trifluoro-acetic acid + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + benzaldehyde (100-52-7) → 4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid (122059-86-3)

Guidance literature:

In acetonitrile; for 3h; Ambient temperature;

DOI:10.1016/S0040-4039(00)82208-X

Reference yield: 83.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + 4-(benzylideneimino)benzoic acid (3939-41-1) → 4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid (122059-86-3)

Guidance literature:

With perchloric acid; triphenylphosphine; In acetonitrile; at 20 ℃; for 0.583333h;

DOI:10.1016/S0040-4020(01)00185-5

Reference yield: 78.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + benzaldehyde (100-52-7) + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid (122059-86-3)

Guidance literature:

With aminosulfonic acid; In methanol; at 20 ℃; for 2h;

upstream raw materials:

cyclopenta-1,3-diene

benzaldehyde

4-nitro-benzoic acid

4-(benzylideneimino)benzoic acid