5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone

Base Information

Chemical Name:5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone
CAS No.:111711-95-6
Molecular Formula:C₁₇H₁₇NO₄S
Molecular Weight:331.392
Hs Code.:
DSSTox Substance ID:DTXSID10920548
Nikkaji Number:J423.515K
Mol file:111711-95-6.mol

Synonyms:111711-95-6;BRN 4760765;5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone;2-Pyrrolidinone, 5-(phenylmethoxy)-1-(phenylsulfonyl)-;5-(PHENYLMETHOXY)-1-(PHENYLSULFONYL)PYRROLIDIN-2-ONE;SCHEMBL9670402;DTXSID10920548;YRZCBUSJFOXKAJ-UHFFFAOYSA-N;LS-138966;1-benzenesulphonyl-2-oxo-5-benzyloxypyrrolidine;5-(Benzyloxy)-1-[(phenyl)sulfonyl]pyrrolidin-2-one;1-(BENZENESULFONYL)-5-(BENZYLOXY)PYRROLIDIN-2-ONE

Suppliers and Price of 5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone

Chemical Property:

Vapor Pressure:9.87E-10mmHg at 25°C
Boiling Point:489.6°C at 760 mmHg
Flash Point:249.9°C
Density:1.36g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:331.08782920
Heavy Atom Count:23
Complexity:501

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1OCC2=CC=CC=C2)S(=O)(=O)C3=CC=CC=C3

Technology Process of 5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone

There total 3 articles about 5-(Phenylmethoxy)-1-(phenylsulfonyl)-2-pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1070-89-9
sodium hexamethyldisilazane

: 111712-08-4
5-benzyloxy-2-pyrrolidinone

: 98-09-9
benzenesulfonyl chloride

: 111711-95-6
1-benzenesulphonyl-2-oxo-5-benzyloxypyrrolidine

Guidance literature:: In diethyl ether; hexane; benzene;

Reference yield:

: 100-51-6,185532-71-2
benzyl alcohol

: 111711-95-6
1-benzenesulphonyl-2-oxo-5-benzyloxypyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / amberlite IR-120 (H⁺ form) / 3 h / 60 - 65 °C

2: 1.) sodium bis(trimethylsilyl)amide / 1.) diethyl ether, 30 min, 2.) diethyl ether, RT, 2 h

With Amberlite IR-120 (H⁺ form); sodium hexamethyldisilazane;
DOI:10.1016/0223-5234(91)90101-R

Reference yield:

: 111712-08-4
5-benzyloxy-2-pyrrolidinone

: 98-09-9
benzenesulfonyl chloride

: 111711-95-6
1-benzenesulphonyl-2-oxo-5-benzyloxypyrrolidine

Guidance literature:: With sodium hexamethyldisilazane; Yield given. Multistep reaction; 1.) diethyl ether, 30 min, 2.) diethyl ether, RT, 2 h;
DOI:10.1016/0223-5234(91)90101-R