2-phenylvinylboronic acid

Base Information

• Chemical Name: 2-phenylvinylboronic acid
• CAS No.: 931430-51-2
• Molecular Formula: C₁₄H₁₇BF₂O₂
• Molecular Weight: 266.096
• Mol file: 931430-51-2.mol

Synonyms:2-phenylvinylboronic acid

Chemical Property of 2-phenylvinylboronic acid

Chemical Property:

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Technology Process of 2-phenylvinylboronic acid

There total 1 articles about 2-phenylvinylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane (288101-48-4) → 2-phenylvinylboronic acid (931430-51-2)

Guidance literature:

With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; water; In tetrahydrofuran; at 90 ℃; for 24h; chemoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1002/chem.201500970

Reference yield: 75.0%

2-phenylvinylboronic acid (931430-51-2) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → C20H30B2F2O4

Guidance literature:

With potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; copper(l) chloride; In toluene; at 23 ℃; for 15h;

DOI:10.1039/c9sc00378a

Reference yield: 60.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-phenylvinylboronic acid (931430-51-2) → trans-2-(2-(2,4-difluorophenyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:

With palladium diacetate; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/c6ob00715e

upstream raw materials:

2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane

Refernces