2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:288101-48-4
Molecular Formula:C12H15 B F2 O2
Molecular Weight:240.058
Hs Code.:2934999090
European Community (EC) Number:622-586-2
DSSTox Substance ID:DTXSID60584472
Nikkaji Number:J3.525.338F
Wikidata:Q82476141
Mol file:288101-48-4.mol

Synonyms:288101-48-4;2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2,4-DIFLUOROPHENYLBORONIC ACID, PINACOL ESTER;2,4-Difluorophenylboronic acid pinacol ester;1,3,2-DIOXABOROLANE, 2-(2,4-DIFLUOROPHENYL)-4,4,5,5-TETRAMETHYL-;C12H15BF2O2;2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1,5-DIFLUOROBENZENE;MFCD05663880;(2,4-DIFLUOROPHENYL)BORONIC ACID PINACOL ESTER;SCHEMBL897058;2,4-DIFLUOROPHENYLBORONIC ACID,PINACOL ESTER;DTXSID60584472;HVKAOYLQBVBZDU-UHFFFAOYSA-N;AKOS015960179;AB22010;AS-49900;SY023640;CS-0153877;EN300-118400;O10034;A876613;2,4-Difluorophenylboronic acid pinacol ester, 97%;J-017275

Suppliers and Price of 2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Difluorophenylboronic acid pinacol ester
1g
$ 75.00

Sigma-Aldrich
2,4-Difluorophenylboronic acid pinacol ester 97%
10g
$ 228.00

Sigma-Aldrich
2,4-Difluorophenylboronic acid pinacol ester 97%
5g
$ 120.00

Matrix Scientific
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
1g
$ 114.00

Matrix Scientific
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
5g
$ 286.00

Crysdot
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
10g
$ 135.00

Crysdot
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
25g
$ 275.00

Crysdot
2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
5g
$ 80.00

AOBChem
2,4-Difluorophenylboronic acid pinacol ester 97%
10g
$ 76.00

AOBChem
2,4-Difluorophenylboronic acid pinacol ester 97%
100g
$ 413.00

Total 35 raw suppliers

Chemical Property of 2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Vapor Pressure:0.00805mmHg at 25°C
Melting Point:41-44 °C(lit.)
Refractive Index:1.468
Boiling Point:276.5°Cat760mmHg
Flash Point:121°C
PSA：18.46000
Density:1.11g/cm³
LogP:2.26400
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:240.1133162
Heavy Atom Count:17
Complexity:280

Purity/Quality:

97% ^*data from raw suppliers

2,4-Difluorophenylboronic acid pinacol ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=C(C=C(C=C2)F)F

Technology Process of 2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 9 articles about 2-(2,4-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 348-57-2
2,4-difluorobromobenzene

: 73183-34-3
bis(pinacol)diborane

: 288101-48-4
2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With DPEPhos; sodium acetate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; for 12h; Heating;
DOI:10.1002/adsc.201500844

Reference yield: 67.0%

: 372-18-9
1,3-Difluorobenzene

: 61676-62-8
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 863868-37-5
2-(2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 288101-48-4
2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: 1,3-Difluorobenzene; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; diisopropylamine; In tetrahydrofuran; at -78 ℃; for 1.66667h; Inert atmosphere;

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; at -78 - 0 ℃; Concentration; Time;
DOI:10.1071/CH13642

Reference yield: 43.0%

: 372-18-9
1,3-Difluorobenzene

: 73183-34-3
bis(pinacol)diborane

: 863868-37-5
2-(2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 288101-48-4
2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: 1,3-Difluorobenzene; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; diisopropylamine; In tetrahydrofuran; at -78 ℃; for 1.66667h; Inert atmosphere;

bis(pinacol)diborane; at -78 - 0 ℃; Concentration; Reagent/catalyst;
DOI:10.1071/CH13642