N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

Base Information

• Chemical Name: N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester
• CAS No.: 1031684-73-7
• Molecular Formula: C₄₃H₆₀N₄O₅S
• Molecular Weight: 745.039
• Mol file: 1031684-73-7.mol

Synonyms:N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

Chemical Property of N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

There total 1 articles about N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-9-fluorenylmethoxycarbonyl-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-72-6) → N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-73-7)

Guidance literature:

With diethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1002/chem.200701634

Reference yield: 84.0%

N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-73-7) + 6-[3,4,5-tris{3-(N-tert-butoxycarbonyl)amino-1-propanoxy}benzoylamino]hexanoic acid (1031684-79-3) → N-(5-{3,4,5-tris[3-N-(tert-butoxycarbonyl)amino-1-propanoxy]benzoylamine}pentanylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-81-7)

Guidance literature:

With (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1002/chem.200701634

Reference yield: 70.0%

N-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-73-7) + 6-[3,4,5-tris(3-N-(tert-butoxycarbonyl)amino-4-phenyl-1-butoxy)benzoylamino]hexanoic acid (1031684-89-5) → N-(5-{3,4,5-tris(3-N-(tert-butoxycarbonyl)amino-4-phenyl-1-butoxy)benzoylamino}pentylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester (1031684-92-0)

Guidance literature:

With (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 17h;

DOI:10.1002/chem.200701634

upstream raw materials:

N-9-fluorenylmethoxycarbonyl-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

Downstream raw materials:

N-(11-{3,4,5-tris[3-N-(tert-butoxycarbonyl)amino-1-propanoxy]benzoylamine}undecanylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

N-(5-{3,4,5-tris[3-N-(tert-butoxycarbonyl)amino-1-propanoxy]benzoylamine}pentanylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

N-(11-{3,4,5-tris(3-N-(tert-butoxycarbonyl)amino-4-phenyl-1-butoxy)benzoylamino}undecanylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester

N-(5-{3,4,5-tris(3-N-(tert-butoxycarbonyl)amino-4-phenyl-1-butoxy)benzoylamino}pentylcarbonyl)-S(trityl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine t-butyl ester