7-Amino-4-hydroxy-2-naphthalenesulfonic acid

Base Information

• Chemical Name: 7-Amino-4-hydroxy-2-naphthalenesulfonic acid
• CAS No.: 87-02-5
• Molecular Formula: C10H9NO4S
• Molecular Weight: 239.252
• Hs Code.: 2922.21
• European Community (EC) Number: 201-718-9
• NSC Number: 31510,8631,7556
• UNII: 9A1IU1C93L
• DSSTox Substance ID: DTXSID7026520
• Nikkaji Number: J356E
• Wikidata: Q259271
• Metabolomics Workbench ID: 127149
• ChEMBL ID: CHEMBL220259
• Mol file: 87-02-5.mol

Synonyms:7-amino-4-hydroxy-2-naphthalenesulfonate;7-amino-4-hydroxy-2-naphthalenesulfonic acid;7-NH2-4-OH-2-NSA

Chemical Property of 7-Amino-4-hydroxy-2-naphthalenesulfonic acid

Chemical Property:

• Appearance/Colour: White needle crystal
• Vapor Pressure: 0Pa at 25℃
• Refractive Index: 1.748
• PKA: -0.28±0.40(Predicted)
• PSA: 109.00000
• Density: 1.627 g/cm³
• LogP: 3.03630
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Slightly soluble in water
• Water Solubility.: 5g/L at 20℃
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 239.02522894
• Heavy Atom Count: 16
• Complexity: 350

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-5-naphthol-7-sulfonic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C(C=C2C=C1N)S(=O)(=O)O)O

Technology Process of 7-Amino-4-hydroxy-2-naphthalenesulfonic acid

There total 4 articles about 7-Amino-4-hydroxy-2-naphthalenesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-amino-naphthalene-1,3-disulfonic acid (118-33-2,87309-33-9) → 7-amino-4-hydroxy-2-naphthalenesulfonic acid (87-02-5)

Guidance literature:

durch Alkalischmelze;

Reference yield:

naphthalene-1,3,6-trisulfonic acid (86-66-8) → 7-amino-4-hydroxy-2-naphthalenesulfonic acid (87-02-5)

Guidance literature:

With sodium hydroxide; anschliessend Erhitzen mit wss. Ammoniak und Schwefeldioxid;

Reference yield:

6-amino-naphthalene-1,3-disulfonic acid (118-33-2,87309-33-9) → 7-amino-4-hydroxy-2-naphthalenesulfonic acid (87-02-5)

Guidance literature:

at 160 - 180 ℃;

upstream raw materials:

6-amino-naphthalene-1,3-disulfonic acid

naphthalene-1,3,6-trisulfonic acid

Downstream raw materials:

AMI-1

4-hydroxy-7-ureido-naphthalene-2-sulfonic acid

7-amino-4-hydroxy-3-phenylazo-naphthalene-2-sulfonic acid

3,7-bis-(6-amino-1-hydroxy-3-sulfo-[2]naphthylazo)-dibenzothiophene-5,5-dioxide