ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Base Information

Chemical Name:ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate
CAS No.:186772-46-3
Molecular Formula:C₂₅H₃₈O₂Si₂
Molecular Weight:426.747
Hs Code.:

Synonyms:ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Suppliers and Price of ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

There total 6 articles about ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 437707-54-5
ethyl 3-bromo-5-[(triisopropylsilyl)ethynyl]benzoate

: 1066-54-2
trimethylsilylacetylene

: 186772-46-3
ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triethylamine; triphenylphosphine; copper(l) iodide; for 16h;
DOI:10.1021/ja012458m

Reference yield:

: 7149-03-3
ethyl 3-bromo-4-aminobenzoate

: 186772-46-3
ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / ICl / acetic acid; H₂O / 10 h / 80 °C

2: 88 percent / NaNO₂; H₂SO₄ / benzene; ethanol / 1.5 h / Heating

3: 99 percent / Pd₂(dba)3*CHCl₃; triphenylphosphine; triethylamine / CuI / 36 h

4: 92 percent / Pd₂(dba)3*CHCl₃; triphenylphosphine; triethylamine / CuI / 16 h

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; sulfuric acid; Iodine monochloride; triethylamine; triphenylphosphine; sodium nitrite; copper(l) iodide; In ethanol; water; acetic acid; benzene;
DOI:10.1021/ja012458m

Reference yield:

: 94-09-7
p-aminoethylbenzoate

: 186772-46-3
ethyl 3-[(trimethylsilyl)ethynyl]-5-[(triisopropylsilyl)ethynyl]benzoate

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / N-bromosuccinimide / CHCl₃ / 4 h / 5 - 10 °C

2: 94 percent / ICl / acetic acid; H₂O / 10 h / 80 °C

3: 88 percent / NaNO₂; H₂SO₄ / benzene; ethanol / 1.5 h / Heating

4: 99 percent / Pd₂(dba)3*CHCl₃; triphenylphosphine; triethylamine / CuI / 36 h

5: 92 percent / Pd₂(dba)3*CHCl₃; triphenylphosphine; triethylamine / CuI / 16 h

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-Bromosuccinimide; sulfuric acid; Iodine monochloride; triethylamine; triphenylphosphine; sodium nitrite; copper(l) iodide; In ethanol; chloroform; water; acetic acid; benzene;
DOI:10.1021/ja012458m