Technology Process of (2S,3S,4S,5S,6S)-4,5-Bis-benzyloxy-2-((S)-1,2-bis-benzyloxy-ethyl)-6-methoxy-tetrahydro-pyran-3-ol
There total 9 articles about (2S,3S,4S,5S,6S)-4,5-Bis-benzyloxy-2-((S)-1,2-bis-benzyloxy-ethyl)-6-methoxy-tetrahydro-pyran-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 28.6 percent / Mg / tetrahydrofuran / 14 h
2: 79.2 percent / NaH (50percent oil susp.) / dimethylformamide / 8 h
3: 87 percent / cerium-ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
With
ammonium cerium(IV) nitrate; sodium hydride; magnesium;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0008-6215(98)00037-8
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 95.1 percent / NaH / dimethylformamide
2: 34 percent / 3 Angstroem molecular sieves, NaBH3CN, Me3SiCl / acetonitrile
3: (COCl)2; Me2SO / CH2Cl2 / 1 h / -60 °C
4: 28.6 percent / Mg / tetrahydrofuran / 14 h
5: 79.2 percent / NaH (50percent oil susp.) / dimethylformamide / 8 h
6: 87 percent / cerium-ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
With
chloro-trimethyl-silane; oxalyl dichloride; ammonium cerium(IV) nitrate; 3 A molecular sieve; sodium hydride; sodium cyanoborohydride; magnesium; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0008-6215(98)00037-8
