1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)-

Base Information

• Chemical Name: 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)-
• CAS No.: 99938-68-8
• Molecular Formula: C₁₂H₂₁N₃O₂S₂
• Molecular Weight: 303.45
• Mol file: 99938-68-8.mol

Synonyms:N-(2-mercaptoethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

Chemical Property of 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)-

Chemical Property:

• Boiling Point: 645.6±50.0 °C(Predicted)
• PKA: 9.78±0.10(Predicted)
• Density: 1.208±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Biotin-Cysteamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)-

There total 8 articles about 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-(2-oxohexahydrothieno[3,4-d]imidazol-4-yl)pentanoic acid (2-{2-[5-(2-oxohexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]ethyldisulfanyl}ethyl)amide (135075-40-0) → N-(2-mercaptoethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide (99938-68-8)

Guidance literature:

With triethylamine; D,L-dithiothreitol; In N,N-dimethyl-formamide; at 22 ℃; for 18h;

DOI:10.1021/jo1008178

Reference yield: 86.0%

2-mercaptoethylamine hydrochloride (156-57-0) + biotin 2,3,5,6-tetrafluorophenyl ester (173341-32-7) → N-(2-mercaptoethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide (99938-68-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 6.75h; Inert atmosphere; Cooling with ice;

DOI:10.5012/bkcs.2011.32.12.4171

Reference yield: 81.0%

C31H35N3O2S2 (1330059-84-1) → N-(2-mercaptoethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide (99938-68-8)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

upstream raw materials:

5-(2-oxohexahydrothieno[3,4-d]imidazol-4-yl)pentanoic acid (2-{2-[5-(2-oxohexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]ethyldisulfanyl}ethyl)amide

C₃₁H₃₅N₃O₂S₂

biotin N-Hydroxysuccinimide ester

Cysteamine

Downstream raw materials:

C₄₈H₇₀N₄O₉S₃

C₄₇H₇₀N₁₂O₁₁S₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 99938-68-8 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-(2-Mercaptoethyl)-2-oxo-, (3aS,4S,6aR)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send