Technology Process of 4-methoxy-3-<(2-methoxypyrid-5-yl)methyl>thiophenol
There total 11 articles about 4-methoxy-3-<(2-methoxypyrid-5-yl)methyl>thiophenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; triphenylphosphine;
In
1,4-dioxane; water;
at 45 ℃;
for 0.5h;
DOI:10.1021/jm00122a009
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) n-BuLi / 1) THF, hexane, -85 deg C, 5 min, 2) THF, below -70 deg C to room temperature
2: pyridine / 50 °C
3: H2 / 10percent Pd/C / methanol
4: 55 percent / Ac2O, Cl2 / acetic acid / 20 h / Ambient temperature
5: 2.55 g / NaOH / dioxane; H2O / 5 h / Heating
With
pyridine; sodium hydroxide; n-butyllithium; hydrogen; acetic anhydride; chlorine;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water; acetic acid;
DOI:10.1021/jm00122a009
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) n-BuLi / 1) THF, hexane, -85 deg C, 5 min, 2) THF, below -70 deg C to room temperature
2: pyridine / 50 °C
3: H2 / 10percent Pd/C / methanol
4: 55 percent / Ac2O, Cl2 / acetic acid / 20 h / Ambient temperature
5: 2.55 g / NaOH / dioxane; H2O / 5 h / Heating
With
pyridine; sodium hydroxide; n-butyllithium; hydrogen; acetic anhydride; chlorine;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water; acetic acid;
DOI:10.1021/jm00122a009
