Technology Process of 1,3-di(hept-6-ynyl)-2-methoxy-5-methylbenzene
There total 5 articles about 1,3-di(hept-6-ynyl)-2-methoxy-5-methylbenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium phosphate monohydrate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere; Schlenk technique
2: tetrabutyl ammonium fluoride; water / tetrahydrofuran / 1 h / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; tetrabutyl ammonium fluoride; water; palladium diacetate;
In
tetrahydrofuran;
1: |Suzuki Coupling;
DOI:10.1002/anie.201206785
- Guidance literature:
-
Multi-step reaction with 3 steps
1: benzyltrimethylammonium tribromide / dichloromethane; methanol / 2 h / Inert atmosphere
2: potassium phosphate monohydrate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere; Schlenk technique
3: tetrabutyl ammonium fluoride; water / tetrahydrofuran / 1 h / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; benzyltrimethylammonium tribromide; tetrabutyl ammonium fluoride; water; palladium diacetate;
In
tetrahydrofuran; methanol; dichloromethane;
2: |Suzuki Coupling;
DOI:10.1002/anie.201206785
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; water;
In
tetrahydrofuran;
for 1h;
Inert atmosphere;
DOI:10.1002/anie.201206785
