4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

Base Information

Chemical Name:4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride
CAS No.:1282042-63-0
Molecular Formula:C₁₆H₁₈N₆OS*ClH
Molecular Weight:378.885
Hs Code.:

Synonyms:4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

Chemical Property:

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Technology Process of 4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

There total 3 articles about 4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1037791-31-3
4-[4-(4-tetrazol-1-ylphenoxymethyl)thiazol-2-yl]piperidine-1-carboxylic acid tert-butyl ester

: 1282042-63-0
4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃; for 7h;

Reference yield:

: 64001-11-2
1-(4-hydroxyphenyl)-1H-1,2,3,4-tetrazole

: 1282042-63-0
4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / Reflux

2: hydrogenchloride / 1,4-dioxane / 7 h / 0 - 20 °C

With hydrogenchloride; caesium carbonate; In 1,4-dioxane; acetonitrile;

Reference yield:

: 650579-82-1
1,1-dimethylethyl 4-[4-(chloromethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate

: 1282042-63-0
4-[4-(4-tetrazol-1-yl-phenoxymethyl)thiazol-2-yl]piperidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / Reflux

2: hydrogenchloride / 1,4-dioxane / 7 h / 0 - 20 °C

With hydrogenchloride; caesium carbonate; In 1,4-dioxane; acetonitrile;