Pyrogallol triacetate

Base Information

• Chemical Name: Pyrogallol triacetate
• CAS No.: 525-52-0
• Molecular Formula: C12H12 O6
• Molecular Weight: 252.224
• Hs Code.: 2915390090
• European Community (EC) Number: 208-374-9
• NSC Number: 24068
• UNII: 4TMC1R26A5
• DSSTox Substance ID: DTXSID10883422
• Nikkaji Number: J6.651F
• Wikidata: Q27260473
• Mol file: 525-52-0.mol

Synonyms:Pyrogallol triacetate;525-52-0;1,2,3-Triacetoxybenzene;Acetpyrogall;Lenigallol;Benzene-1,2,3-triyl triacetate;Pyracetol;Pyrogallol, triacetate;Triacetylpyrogallol;1,2,3-BENZENETRIOL, TRIACETATE;NSC 24068;(2,3-diacetyloxyphenyl) acetate;1,2,3-Benzenetriol, 1,2,3-triacetate;2,3-Bis(acetyloxy)phenyl acetate;UNII-4TMC1R26A5;4TMC1R26A5;EINECS 208-374-9;NSC-24068;AI3-03113;1,2,3-Phenenyl triacetate;1,3-Benzenetriol, triacetate;Benzene-1,2,3-triyltriacetate;SCHEMBL5212814;DTXSID10883422;HMS1718I07;PYROGALLOL TRIACETATE [MI];NSC24068;MFCD00017220;AKOS001064238;1,2,3-TRIACETYLBENZENETRIOLATE;FT-0632292;SR-01000054286;SR-01000054286-1;Q27260473;Z56995298

Chemical Property of Pyrogallol triacetate

Chemical Property:

• Vapor Pressure: 2.43E-05mmHg at 25°C
• Melting Point: 165-167°C
• Boiling Point: 309°Cat760mmHg
• Flash Point: 164.4°C
• PSA: 78.90000
• Density: 1.488g/cm³
• LogP: 1.46250
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 252.06338810
• Heavy Atom Count: 18
• Complexity: 314

Purity/Quality:

98%min ^*data from raw suppliers

1,2,3-TRIACETOXYBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=C(C(=CC=C1)OC(=O)C)OC(=O)C
• Uses: Developer in photography; making colloidal solutions of metals; as mordant for wool, staining leather, process engraving; manufacture of various dyes; dyeing furs, hair, etc.; in analytical chemistry as a reagent for antimony and bismuth; as an active reducer for gold, silver and mercury salts; especially for absorption of oxygen in gas analysis.

Technology Process of Pyrogallol triacetate

There total 10 articles about Pyrogallol triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic anhydride (108-24-7) + 2-hydroxyresorcinol (87-66-1) → pyrogallol triacetate (525-52-0)

Guidance literature:

With magnesium(II) perchlorate; at 20 ℃; for 0.25h;

DOI:10.1016/j.tet.2003.08.007

Reference yield: 98.0%

1,2,3-trimethoxybenzene (634-36-6) + acetic acid (64-19-7,77671-22-8) → pyrogallol triacetate (525-52-0)

Guidance literature:

1,2,3-trimethoxybenzene; With boron tribromide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

acetic acid; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.3184/174751912X13324176277811

Reference yield: 94.0%

acetic acid (64-19-7,77671-22-8) + 2-hydroxyresorcinol (87-66-1) → pyrogallol triacetate (525-52-0)

Guidance literature:

With poly(4-vinylpyridine) perchlorate; In neat (no solvent); at 20 ℃; for 0.75h;

DOI:10.1016/j.molcata.2012.05.021

upstream raw materials:

4,5,6-trihydroxyisophthalic acid

potassium acetate

acetic anhydride

2-hydroxyresorcinol

Downstream raw materials:

2',3',4'-trihydroxyacetophenone

6-acetyl-2,3-diacetoxyphenol

3-acetoxy-pyrocatechol

4-Nitropyrogallol-1.2-diacetat

Refernces

• 1、 Degotte, Gilles,Francotte, Pierre,Pirotte, Bernard,Frédérich, Michel. "Polyhydroxybenzoic acid derivatives as potential new antimalarial agents". . . Retrieved 2021/08/07.
• 2、 Khaligh, Nader Ghaffari,Mihankhah, Taraneh,Johan, Mohd Rafie,Juan, Joon Ching. "4-Imidazol-1-yl-butane-1-sulfonic acid ionic liquid: Synthesis, structural analysis, physical properties and catalytic application as dual solvent-catalyst". . p. 866 - 878. Retrieved 2019/07/12.