Potassium acetate

Base Information

• Chemical Name: Potassium acetate
• CAS No.: 127-08-2
• Molecular Formula: C2H3KO2
• Molecular Weight: 98.1429
• Hs Code.: 29159000
• Mol file: 127-08-2.mol

Synonyms:Polycat 46;Acetic acid,compounds,potassium salt;Catacyst LB;Kaliumazetat;Potassium Acetate, Granular, U.S.P.;Acetic acid, potassium salt;

Chemical Property of Potassium acetate

Chemical Property:

• Appearance/Colour: colourless crystals or white powder
• Vapor Pressure: 13.9mmHg at 25°C
• Melting Point: 292 °C
• Refractive Index: n20/D 1.370
• Boiling Point: 117.1oC at 760 mmHg
• PKA: 4.756[at 20 ℃]
• Flash Point: 40oC
• PSA: 40.13000
• Density: 1.57 g/cm³
• LogP: -1.24380
• Storage Temp.: Store at RT.
• Sensitive.: Hygroscopic
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: 2694 g/L (25 ºC)

Purity/Quality:

99.0%~100.5% ^*data from raw suppliers

Potassium Acetate, ACS ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,T
• Hazard Codes: Xi,T
• Statements: 36/37/38-25-23/24/25-21
• Safety Statements: 26-36-24/25-45-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• General Description: Potassium acetate (KOAc) is an inorganic base commonly used in catalytic reactions, such as palladium-catalyzed C–P coupling, where it serves as a base to facilitate the formation of reactive intermediates and enhance reaction efficiency. It is also employed in the study of rhodium(III) porphyrin reactivity with methanol, demonstrating its utility in promoting carbon-oxygen bond cleavage and supporting high-yield transformations. Potassium acetate is valued for its role in organic synthesis, particularly in reactions requiring mild basic conditions.

Technology Process of Potassium acetate

There total 99 articles about Potassium acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium 4-nitrophenolate (1124-31-8) + acetic acid (64-19-7,77671-22-8) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + potassium acetate (127-08-2)

Guidance literature:

In acetonitrile; at 20 ℃; Equilibrium constant; Further equilibria;

DOI:10.1021/ac00263a041

Reference yield:

3-benzyl-1,2-dimethylimidazolium bromide (862999-80-2) → potassium acetate (127-08-2) + methylamine (74-89-5) + benzylamine (100-46-9)

Guidance literature:

With 1,1,1-trideuteromethanol; potassium hydroxide; at 80 ℃;

DOI:10.1021/acs.joc.0c02051

Reference yield:

4-bromonaphthalen-1-yl acetate (203204-53-9) → 4-bromo-1-naphthol (571-57-3) + potassium acetate (127-08-2)

Guidance literature:

With potassium hydroxide; potassium chloride; at 20 ℃; Further Variations:; Temperatures; Kinetics;

upstream raw materials:

acetic acid

4-acetoxy azetidinone

vinyl crotonate

mercury(II) diacetate

Downstream raw materials:

1,2,5-triacetoxypentane

2,5-dihydro-2,5-dimethoxyfuran

2-Acetoxy-5-methoxy-2,5-dihydro-furan

4,6-dioxopyrimido-2,1,3-thiadiazole

Refernces

Reactivity studies of rhodium(III) porphyrins with methanol in alkaline media

10.1021/om801029k

The research investigates the reaction of Rhodium(III) porphyrins (specifically Rh(ttp)Cl) with methanol in the presence of inorganic bases at high temperatures (150 °C) to produce rhodium porphyrin methyls (Rh(ttp)CH3) with high yields (up to 87%). The study aims to understand the carbon-hydrogen bond activation chemistry of rhodium porphyrins and to explore the conditions under which methanol can react with these complexes to aid in the design of catalysts for catalytic methane oxidation. The key findings suggest that Rh(ttp)H is the key intermediate for carbon-oxygen bond cleavage, and the role of bases is to facilitate the formation of reactive intermediates and enhance reaction rates. The research concludes that to achieve efficient rhodium porphyrin-based methane oxidation, it would be necessary to either continuously remove methanol or carry out the reaction at lower conversions. The key chemicals used in the research include Rh(ttp)Cl (rhodium(III) tetrakistolylporphyrinato chloride), methanol, various inorganic bases (such as KOH, NaOH, K2CO3, Na2CO3, Potassium bicarbonate (KHCO3), K3PO4, Potassium acetate (KOAc), and Sodium acetate (NaOAc)), and other rhodium porphyrin complexes like Rh(tpp)Cl, Rh(tmp)Cl, and Rh2(ttp)2.

Catalytic palladium phosphination: Modular synthesis of C ₁-symmetric biaryl-based diphosphines

10.1002/chem.201101529

The research focuses on the development of a novel synthetic methodology for the preparation of C1-symmetric bis(diphenylphosphino)biphenyl ligands, which are crucial in asymmetric catalysis. The study aimed to overcome the challenges associated with the synthesis of these ligands, particularly the undesired intramolecular cyclization leading to phosphafluorene formation. The researchers successfully developed a palladium-catalyzed C–P coupling reaction that does not require additional ligands and avoids the formation of phosphafluorene in most cases. This method allows for the rapid synthesis of a variety of substituted ortho,ortho'-bis(diphenylphosphino)biphenyls in moderate-to-excellent yields and significantly reduced reaction times compared to previous methods. Key chemicals used in the process include ortho,ortho’-dihalobiphenyl precursors, diphenylphosphine (HPPh2), palladium acetate (Pd(OAc)2) as the catalyst, potassium acetate (KOAc) as the base, and N,N-dimethylacetamide (DMA) as the solvent. The study's conclusions open new pathways for the synthesis of more complex diphosphines based on C1- or C2-symmetric biaryl scaffolds and has implications for the direct synthesis of enantiomerically pure C1-symmetric biaryl-based diphosphines.