(2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane

Base Information

• Chemical Name: (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane
• CAS No.: 784178-00-3
• Molecular Formula: C₃₄H₃₉N₃O₅S₂
• Molecular Weight: 633.833
• Mol file: 784178-00-3.mol

Synonyms:(2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane

Chemical Property of (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane

There total 2 articles about (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(2S,6S)-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane + acetic acid (64-19-7,77671-22-8) → (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane (784178-00-3)

Guidance literature:

With dmap; triethylamine; p-toluenesulfonyl chloride; In dichloromethane; for 18h;

DOI:10.1039/b409259g

Reference yield:

(2S,6S)-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane + acetic anhydride (108-24-7) → (2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane (784178-00-3)

Guidance literature:

for 4h; Heating;

DOI:10.1039/b409259g

Reference yield: 62.0%

(2S,6S)-4-acetyl-1,7-di-p-toluenesulfonyl-2,6-dibenzyl-1,4,7-triazaheptane (784178-00-3) + 1,2-bis-tosyloxyethane (6315-52-2) → (2S,6S)-4-acetyl-2,6-dibenzyl-1,7-di-p-toluenesulfonyl-1,4,7-triazacyclononane

Guidance literature:

With caesium carbonate; In acetonitrile; for 144h; Heating;

DOI:10.1039/b409259g

upstream raw materials:

acetic anhydride

acetic acid