1-(Aminomethyl)cyclopentanamine

Base Information

• Chemical Name: 1-(Aminomethyl)cyclopentanamine
• CAS No.: 5062-66-8
• Molecular Formula: C6H14N2
• Molecular Weight: 114.19
• Hs Code.: 2921300090
• UNII: ZZ84YT3UHF
• DSSTox Substance ID: DTXSID30198666
• Nikkaji Number: J48.271D
• Wikidata: Q83071491
• Mol file: 5062-66-8.mol

Synonyms:5062-66-8;1-(Aminomethyl)cyclopentanamine;1-(aminomethyl)cyclopentan-1-amine;Cyclopentanemethanamine, 1-amino-;1-Aminocyclopentane-1-methanamine;1-Aminomethylcyclopentylamine;BRN 2801629;Amino-1 aminomethyl-1 cyclopentane;1-(aminomethyl)cyclopentylamine;Cyclopentylamine, 1-aminomethyl-;[(1-aminocyclopentyl)methyl]amine;Cyclopentanemethanamine, 1-amino- (9CI);ZZ84YT3UHF;SCHEMBL76443;1-aminomethyl-cyclopentylamine;DTXSID30198666;AMY40946;1-AMINOCYCLOPENTANEMETHANAMINE;MFCD01735696;AKOS009358091;BS-12109;LS-58429;EN300-58507;65789-80-2

Chemical Property of 1-(Aminomethyl)cyclopentanamine

Chemical Property:

• Vapor Pressure: 2.62mmHg at 25°C
• Boiling Point: 158.5°C at 760 mmHg
• Flash Point: 55.3°C
• PSA: 52.04000
• Density: 0.955g/cm³
• LogP: 1.61720
• Storage Temp.: 2-8°C
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 114.115698455
• Heavy Atom Count: 8
• Complexity: 74.6

Purity/Quality:

>97%, ^*data from raw suppliers

1-(Aminomethyl)cyclopentanamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)(CN)N

Technology Process of 1-(Aminomethyl)cyclopentanamine

There total 11 articles about 1-(Aminomethyl)cyclopentanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1-(aminomethyl)-N-benzylcyclopentanamine (1383777-45-4) → 1-(aminomethyl)cyclopentanamine (5062-66-8)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; acetic acid; In methanol; at 30 ℃; for 24h; under 5250.53 Torr;

Reference yield: 13.0%

1-amino-1-(nitromethyl)cyclopentane (1204616-80-7) → 1-(aminomethyl)cyclopentanamine (5062-66-8)

Guidance literature:

1-amino-1-(nitromethyl)cyclopentane; With potassium hydroxide; hydrogen; nickel; In methanol; at 20 ℃; for 16h; under 760.051 Torr;

With hydrogenchloride; In methanol; water;

With sodium hydroxide; In water;

Reference yield:

(1-aminomethylcyclopentyl)carbamic acid tert-butyl ester (889949-09-1) → 1-(aminomethyl)cyclopentanamine (5062-66-8)

Guidance literature:

(1-aminomethylcyclopentyl)carbamic acid tert-butyl ester; With trimethylsilyl iodide; In DCM;

With methanol; In dichloromethane;

upstream raw materials:

N-(1-cyanocyclopentyl)acetamide

cyclopentanone

1-amino-1-(nitromethyl)cyclopentane

(1-cyanocyclopentyl)-carbamic acid tert-butyl ester

Downstream raw materials:

1-((dimethylamino)methyl)-N,N-dimethylcyclopentanamine

1,3-diaza-spiro[4.4]nonane-2-thione

Refernces

• 1、 -. "Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases". Paragraph 2488. . Retrieved 2015/09/22.
• 2、 -. "COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES". . . Retrieved 2012/04/23.