3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester

Base Information

• Chemical Name: 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester
• CAS No.: 209665-37-2
• Molecular Formula: C₁₅H₂₁NO₃
• Molecular Weight: 263.337
• Mol file: 209665-37-2.mol

Synonyms:3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester

Chemical Property of 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester

There total 2 articles about 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

→ 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester (209665-37-2)

Guidance literature:

Reference yield:

4-(Diethylamino)salicylaldehyde (17754-90-4) + diethyl malonate (105-53-3) → 3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester (209665-37-2)

Guidance literature:

With piperidine; In ethanol; for 6h; Reflux;

DOI:10.1039/c1dt10490j

Reference yield: 85.0%

3-(4-diethylamino-2-hydroxyphenyl)-2-propenic acid ethyl ester (209665-37-2) + Diphenyliodonium triflate (66003-76-7) → 7-(N,N-diethylamino)-4-phenyl-2H-chromen-2-one (154869-90-6)

Guidance literature:

With palladium diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2015.04.082

upstream raw materials:

4-(Diethylamino)salicylaldehyde

diethyl malonate

Downstream raw materials:

7-diethylamino-2H-benzopyran-2-one

7-(N,N-diethylamino)-4-phenyl-2H-chromen-2-one