6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

Base Information

Chemical Name:6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester
CAS No.:737767-79-2
Molecular Formula:C₃₆H₃₉N₃O₇
Molecular Weight:625.722
Hs Code.:

6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid <i>tert</i>-butyl ester

Synonyms:6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

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Chemical Property of 6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

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Technology Process of 6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

There total 4 articles about 6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 737767-10-1
hydroxy-(4-hydroxy-phenyl)-acetic acid allyl ester

: 737767-79-2
6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: iPr₂NEt

2: Pd(PPh₃)4; acetic acid; N-methylalanine

3: EDC; DMAP

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-methylalanine; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine;
DOI:10.1002/anie.200353204

Reference yield:

: 737767-12-3
hydroxy-(4-phenylacetoxy-phenyl)-acetic acid allyl ester

: 737767-79-2
6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Pd(PPh₃)4; acetic acid; N-methylalanine

2: EDC; DMAP

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-methylalanine; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1002/anie.200353204

Reference yield:

: 697226-47-4
(4-phenylacetoxy-phenyl)-(quinolin-6-ylcarbamoyloxy)-acetic acid allyl ester

: 737767-79-2
6-[2-(4-phenylacetoxy-phenyl)-2-(quinolin-6-ylcarbamoyloxy)-acetylamino]-hexanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)4; acetic acid; N-methylalanine

2: EDC; DMAP

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-methylalanine; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1002/anie.200353204