1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione

Base Information

Chemical Name:1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione
CAS No.:79323-05-0
Molecular Formula:C₂₅H₃₀ClN₃O₃
Molecular Weight:455.984
Hs Code.:
DSSTox Substance ID:DTXSID90229627
Wikidata:Q83109925

Synonyms:1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione;2,6-Piperidinedione, 1-(3-(4-(2-chlorophenyl)-1-piperazinly)propyl)-4-(4-methoxyphenyl)-;79323-05-0;C25H30ClN3O3;DTXSID90229627;LS-115197

Suppliers and Price of 1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione

Chemical Property:

Vapor Pressure:2.25E-16mmHg at 25°C
Boiling Point:642°C at 760 mmHg
Flash Point:342.1°C
Density:1.22g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:455.1975695
Heavy Atom Count:32
Complexity:614

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2CC(=O)N(C(=O)C2)CCCN3CCN(CC3)C4=CC=CC=C4Cl

Technology Process of 1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione

There total 3 articles about 1-(3-(4-(2-Chlorophenyl)-1-piperazinyl)propyl)-4-(4-methoxyphenyl)-2,6-piperidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39512-50-0
N-(o-Chlorophenyl)piperazine

: 79323-05-0
1-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propyl}-4-(4-methoxy-phenyl)-piperidine-2,6-dione

Guidance literature:: Multi-step reaction with 3 steps

1: Heating

2: hydrogen, NH₃ / Raney-Ni / methanol / 2585.7 Torr / Ambient temperature

3: 2.) Ac₂O / 1.) pyridine, heating, 15 h; 2.) heating, 5-6 h

With ammonia; hydrogen; acetic anhydride; nickel; In methanol;

Reference yield:

: 75426-51-6
3-[4-(2-chlorophenyl)-piperazin-1-yl]-propionitrile

: 79323-05-0
1-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propyl}-4-(4-methoxy-phenyl)-piperidine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen, NH₃ / Raney-Ni / methanol / 2585.7 Torr / Ambient temperature

2: 2.) Ac₂O / 1.) pyridine, heating, 15 h; 2.) heating, 5-6 h

With ammonia; hydrogen; acetic anhydride; nickel; In methanol;