ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate

Base Information

• Chemical Name: ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate
• CAS No.: 1019777-12-8
• Molecular Formula: C₁₅H₁₇O₃P
• Molecular Weight: 276.272
• Mol file: 1019777-12-8.mol

Synonyms:ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate

Chemical Property of ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate

There total 2 articles about ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 1-butyryloxy-1-phenylmethane(P-phenyl)phosphinate (866612-47-7) → ethyl (SP,S)-hydroxy(phenyl)methane(P-phenyl)phosphinate + ethyl (SP,R)-hydroxy(phenyl)methane(P-phenyl)phosphinate + ethyl (RP,S)-hydroxy(phenyl)methane(P-phenyl)phosphinate (918154-55-9) + ethyl (SP,R)-butyryloxy(phenyl)methane(P-phenyl)phosphinate + ethyl (RP,R)-butyryloxy(phenyl)methane(P-phenyl)phosphinate + ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate (1019777-12-8) + ethyl 1-butyryloxy-1-phenylmethane(P-phenyl)phosphinate + ethyl 1-butyryloxy-1-phenylmethane(P-phenyl)phosphinate

Guidance literature:

With Escherichia coli; In aq. phosphate buffer; at 20 ℃; for 19h; pH=7; Reagent/catalyst; Time; enantioselective reaction; Microbiological reaction;

DOI:10.1080/10426507.2019.1599890

Reference yield:

ethyl (RSP,RS)-butyryloxy(phenyl)methane(P-phenyl)phosphinate → ethyl (SP,S)-hydroxy(phenyl)methane(P-phenyl)phosphinate + ethyl (RP,R)-butyryloxy(phenyl)methane(P-phenyl)phosphinate + ethyl (R(P),R)-1-hydroxy(phenyl)methane(P-phenyl)phosphinate (1019777-12-8)

Guidance literature:

With Candida cylinracea lipase; water; lithium chloride; In di-isopropyl ether; at 20 ℃; for 48h; optical yield given as %ee; Enzymatic reaction;

DOI:10.1080/10426500903365595

upstream raw materials:

ethyl 1-butyryloxy-1-phenylmethane(P-phenyl)phosphinate