C₃₄H₄₆O₅

Base Information

• Chemical Name: C₃₄H₄₆O₅
• CAS No.: 1186505-20-3
• Molecular Formula: C₃₄H₄₆O₅
• Molecular Weight: 534.736
• Mol file: 1186505-20-3.mol

Synonyms:C₃₄H₄₆O₅

Chemical Property of C₃₄H₄₆O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₄₆O₅

There total 11 articles about C₃₄H₄₆O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

C28H40O (1186505-18-9) + dimethyl acetylenedicarboxylate (762-42-5) → C34H46O5 (1186505-20-3) + C34H46O5 (1186505-19-0)

Guidance literature:

at 110 ℃; for 24h; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.06.064

Reference yield:

C20H34O (1318052-00-4) → C34H46O5 (1186505-20-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h / -60 °C / Inert atmosphere

1.2: 0.17 h / -60 °C / Inert atmosphere

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 °C

3.1: pyrrolidine / diethyl ether / 20 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / 0 °C / Inert atmosphere

4.2: 8 h / 0 - 20 °C / Inert atmosphere

5.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 - 20 °C / Inert atmosphere

5.2: 0 - 35 °C / Inert atmosphere

6.1: 24 h / 110 °C / Inert atmosphere

With pyrrolidine; n-butyllithium; oxalyl dichloride; sodium hydride; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 1.1: Swern oxidation / 1.2: Swern oxidation / 4.2: Wittig reaction / 6.1: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.05.092

Reference yield:

C21H34O2 (1318051-97-6) → C34H46O5 (1186505-20-3)

Guidance literature:

Multi-step reaction with 7 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 6 h / 0 °C

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h / -60 °C / Inert atmosphere

2.2: 0.17 h / -60 °C / Inert atmosphere

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 °C

4.1: pyrrolidine / diethyl ether / 20 °C

5.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / 0 °C / Inert atmosphere

5.2: 8 h / 0 - 20 °C / Inert atmosphere

6.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 - 20 °C / Inert atmosphere

6.2: 0 - 35 °C / Inert atmosphere

7.1: 24 h / 110 °C / Inert atmosphere

With pyrrolidine; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; sodium hydride; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 2.1: Swern oxidation / 2.2: Swern oxidation / 5.2: Wittig reaction / 7.1: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.05.092

upstream raw materials:

C₂₈H₄₀O

dimethyl acetylenedicarboxylate

C₂₁H₃₄O

C₂₁H₃₂O

Downstream raw materials:

C₃₂H₄₂O₃

C₃₂H₄₆O₃

C₃₂H₄₂O₂