(R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate

Base Information

Chemical Name:(R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate
CAS No.:1046783-92-9
Molecular Formula:C₁₈H₁₇IN₂O₅
Molecular Weight:468.248
Hs Code.:

Synonyms:(R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate

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Chemical Property of (R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate

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Technology Process of (R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate

There total 1 articles about (R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 928056-41-1
methyl (2E)-3-chloro-2-iodoacrylate

: 195834-11-8
tert-butyl 2-(benzyloxycarbonylamino)-2-cyanoacetate

: C₁₈H₁₇IN₂O₅

: 1046783-92-9
(R)-1-benzyl 2-tert-butyl 2-cyano-4-iodo-5-oxo-1H-pyrrole-1,2(2H,5H)-dicarboxylate

Guidance literature:: With (1S,3R,4S,8R,9S)-1-((10-cyanoanthracen-9-yl)methyl)-8-ethyl-2-(hydroxy(quinolin-4-yl)methyl)-1-azoniabicyclo[2.2.2]octane bromide; potassium carbonate; In water; toluene; at -30 ℃; for 17h; optical yield given as %ee;
DOI:10.1002/anie.200800329