Technology Process of C11H14O5
There total 1 articles about C11H14O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3-Methoxy-5-methoxymethoxy-phenyl)-methanol;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
Inert atmosphere;
N,N-dimethyl-formamide;
With
calcium hydride;
In
tetrahydrofuran; hexane;
at -30 ℃;
Inert atmosphere;
With
water; ammonium chloride;
In
tetrahydrofuran; hexane;
Saturated solution;
DOI:10.1016/j.bmc.2010.07.056
- Guidance literature:
-
With
15-crown-5; sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
Inert atmosphere;
DOI:10.1016/j.bmc.2010.07.056
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium hydride / 15-crown-5 / tetrahydrofuran / 0.13 h / 20 °C
2: methanesulfonyl chloride; triethylamine / tetrahydrofuran / 0.83 h / 20 °C
3: sodium iodide / acetone / 1 h / 20 °C / Darkness
4: N,N-dimethyl-formamide / 20.5 h / 115 °C
5: sodium hydride / 15-crown-5 / tetrahydrofuran / 1.08 h / 20 °C
6: ammonium chloride; zinc / acetone / 1.5 h / Reflux
With
sodium hydride; ammonium chloride; methanesulfonyl chloride; triethylamine; sodium iodide; zinc;
15-crown-5;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetone;
4: Arbuzov Reaction / 5: Horner- Wadsworth-Emmons reaction;
