C₃₁H₄₃NO₃Si

Base Information

• Chemical Name: C₃₁H₄₃NO₃Si
• CAS No.: 498542-74-8
• Molecular Formula: C₃₁H₄₃NO₃Si
• Molecular Weight: 505.773
• Mol file: 498542-74-8.mol

Synonyms:C₃₁H₄₃NO₃Si

Chemical Property of C₃₁H₄₃NO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₄₃NO₃Si

There total 10 articles about C₃₁H₄₃NO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C32H43NO4Si (498542-72-6) → C31H43NO3Si (498542-74-8)

Guidance literature:

With lithium borohydride; In methanol; diethyl ether; Heating;

DOI:10.1016/S0960-894X(02)00373-6

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C31H43NO3Si (498542-74-8)

Guidance literature:

Multi-step reaction with 9 steps

1: 100 percent / imidazole; 4-DMAP / CH₂Cl₂ / 20 °C

2: 100 percent / H₂ / PtO₂ / ethanol / 20 °C

3: 100 percent / LiAlH₄ / tetrahydrofuran / 20 °C

4: 100 percent / Et₃N / CH₂Cl₂ / 20 °C

5: 100 percent / BF₃*OEt₂ / diethyl ether / -78 °C

6: 95 percent / I₂; Ph₃P; imidazole / benzene / 20 °C

7: 95 percent / LDA / tetrahydrofuran / -78 °C

8: 100 percent / LDA / tetrahydrofuran / -78 °C

9: 82 percent / LiBH₄ / diethyl ether; methanol / Heating

With 1H-imidazole; dmap; lithium aluminium tetrahydride; lithium borohydride; boron trifluoride diethyl etherate; hydrogen; iodine; triethylamine; triphenylphosphine; lithium diisopropyl amide; platinum(IV) oxide; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; benzene;

DOI:10.1016/S0960-894X(02)00373-6

Reference yield:

[(1S,5S)-1-Hydroxymethyl-6-aza-spiro[4.5]dec-(7Z)-ylidene]-acetic acid ethyl ester → C31H43NO3Si (498542-74-8)

Guidance literature:

Multi-step reaction with 9 steps

1: 100 percent / imidazole; 4-DMAP / CH₂Cl₂ / 20 °C

2: 100 percent / H₂ / PtO₂ / ethanol / 20 °C

3: 100 percent / LiAlH₄ / tetrahydrofuran / 20 °C

4: 100 percent / Et₃N / CH₂Cl₂ / 20 °C

5: 100 percent / BF₃*OEt₂ / diethyl ether / -78 °C

6: 95 percent / I₂; Ph₃P; imidazole / benzene / 20 °C

7: 95 percent / LDA / tetrahydrofuran / -78 °C

8: 100 percent / LDA / tetrahydrofuran / -78 °C

9: 82 percent / LiBH₄ / diethyl ether; methanol / Heating

With 1H-imidazole; dmap; lithium aluminium tetrahydride; lithium borohydride; boron trifluoride diethyl etherate; hydrogen; iodine; triethylamine; triphenylphosphine; lithium diisopropyl amide; platinum(IV) oxide; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; benzene;

DOI:10.1016/S0960-894X(02)00373-6

upstream raw materials:

C₃₂H₄₃NO₄Si

tert-butylchlorodiphenylsilane

2-[(1S,5S,7R)-1-(tert-Butyl-diphenyl-silanyloxymethyl)-6-aza-spiro[4.5]dec-7-yl]-ethanol

C₂₉H₃₉NO₃Si